Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's lymphoma,
is clinically heterogeneous: 40% of patients respond well to current therapy and have …
is clinically heterogeneous: 40% of patients respond well to current therapy and have …
[HTML][HTML] The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
A Rosenwald, G Wright, WC Chan… - … England Journal of …, 2002 - Mass Medical Soc
Background The survival of patients with diffuse large-B-cell lymphoma after chemotherapy
is influenced by molecular features of the tumors. We used the gene-expression profiles of …
is influenced by molecular features of the tumors. We used the gene-expression profiles of …
Oncogenically active MYD88 mutations in human lymphoma
…, P Romesser, G Wright, J Powell, A Rosenwald… - Nature, 2011 - nature.com
The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) remains
the least curable form of this malignancy despite recent advances in therapy 1 . Constitutive …
the least curable form of this malignancy despite recent advances in therapy 1 . Constitutive …
[HTML][HTML] The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms
…, SV Rajkumar, AC Rawstron, K Rech, A Rosenwald… - Leukemia, 2022 - nature.com
We herein present an overview of the upcoming 5 th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray
Diffuse large B-cell lymphoma (DLBCL) can be divided into prognostically important
subgroups with germinal center B-cell–like (GCB), activated B-cell–like (ABC), and type 3 gene …
subgroups with germinal center B-cell–like (GCB), activated B-cell–like (ABC), and type 3 gene …
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
…, M Castoldi, J Soutschek, V Koteliansky, A Rosenwald… - Nature, 2008 - nature.com
MicroRNAs comprise a broad class of small non-coding RNAs that control expression of
complementary target messenger RNAs 1 , 2 . Dysregulation of microRNAs by several …
complementary target messenger RNAs 1 , 2 . Dysregulation of microRNAs by several …
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
A role for B-cell-receptor (BCR) signalling in lymphomagenesis has been inferred by studying
immunoglobulin genes in human lymphomas 1 , 2 and by engineering mouse models 3 , …
immunoglobulin genes in human lymphomas 1 , 2 and by engineering mouse models 3 , …
[HTML][HTML] Genetics and pathogenesis of diffuse large B-cell lymphoma
…, A Lopez-Guillermo, A Rosenwald… - New England journal …, 2018 - Mass Medical Soc
Background Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B-cell…
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B-cell…
[HTML][HTML] Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
SS Dave, G Wright, B Tan, A Rosenwald… - … England Journal of …, 2004 - Mass Medical Soc
Background Patients with follicular lymphoma may survive for periods of less than 1 year to
more than 20 years after diagnosis. We used gene-expression profiles of tumor-biopsy …
more than 20 years after diagnosis. We used gene-expression profiles of tumor-biopsy …
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
A Rosenwald, AA Alizadeh, G Widhopf… - The Journal of …, 2001 - rupress.org
The most common human leukemia is B cell chronic lymphocytic leukemia (CLL), a malignancy
of mature B cells with a characteristic clinical presentation but a variable clinical course. …
of mature B cells with a characteristic clinical presentation but a variable clinical course. …