SPACE–a randomized study of SBRT vs conventional fractionated radiotherapy in medically inoperable stage I NSCLC

J Nyman, A Hallqvist, JÅ Lund, OT Brustugun… - Radiotherapy and …, 2016 - Elsevier
Background Stereotactic body radiotherapy (SBRT) has been introduced for small lung tumors
due to excellent local control and few side effects, even though there are no comparative …

[HTML][HTML] Phase II trial demonstrates the efficacy and safety of individualized, dosimetry-based 177Lu-DOTATATE treatment of NET patients

…, CF Warfvinge, K Holgersson, A Hallqvist… - European journal of …, 2022 - Springer
Purpose Radionuclide therapy with 177 Lu-DOTATATE is well established for patients with
advanced somatostatin receptor–positive neuroendocrine tumors with a standard schedule …

[HTML][HTML] Astatine-211 based radionuclide therapy: Current clinical trial landscape

P Albertsson, T Bäck, K Bergmark, A Hallqvist… - Frontiers in …, 2023 - frontiersin.org
Astatine-211 (211At) has physical properties that make it one of the top candidates for use
as a radiation source for alpha particle-based radionuclide therapy, also referred as targeted …

Intraperitoneal α-Emitting radioimmunotherapy with 211AT in relapsed ovarian cancer: long-term follow-up with individual absorbed dose estimations

A Hallqvist, K Bergmark, T Bäck… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Eliminating microscopic residual disease with α-particle radiation is theoretically appealing.
After extensive preclinical work with α-particle–emitting 211 At, we performed a phase I trial …

Positron emission tomography and computed tomographic imaging (PET/CT) for dose planning purposes of thoracic radiation with curative intent in lung cancer …

A Hallqvist, C Alverbratt, A Strandell… - Radiotherapy and …, 2017 - Elsevier
Background and purpose PET/CT is a proposed management to improve the accuracy of high
dose radiochemotherapy in lung cancer patients. This systematic review was performed to …

[HTML][HTML] KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer

…, LM Akyürek, S Raghavan, J Nyman, A Hallqvist… - Cancers, 2022 - mdpi.com
Simple Summary In this retrospective study including 580 patients with metastatic (Stage IV)
non-small cell lung cancer, we investigated whether KRAS mutational status had any impact …

Specific uptake in the bone marrow causes high absorbed red marrow doses during [177Lu] Lu-DOTATATE treatment

J Hemmingsson, J Svensson, A Hallqvist… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Bone marrow suppression is a common side effect after [ 177 Lu]Lu-DOTATATE treatment of
neuroendocrine neoplasms. Neuroendocrine neoplasms share expression of somatostatin …

Immune checkpoint blockade and biomarkers of clinical response in non–small cell lung cancer

A Hallqvist, A Rohlin… - Scandinavian journal of …, 2020 - Wiley Online Library
Immunotherapy with PD‐1 and PD‐L1 inhibitors has revolutionized the treatment for patients
with NSCLC the last years with increased overall survival and in particular increased …

Health related quality of life in locally advanced NSCLC treated with high dose radiotherapy and concurrent chemotherapy or cetuximab–pooled results from two …

A Hallqvist, B Bergman, J Nyman - Radiotherapy and Oncology, 2012 - Elsevier
BACKGROUND: In non-small cell lung cancer (NSCLC) stage III, data on patient reported
health-related quality of life (HRQL) are scarce, especially regarding concurrent …

[HTML][HTML] KRAS G12C Mutant Non–Small Cell Lung Cancer Linked to Female Sex and High Risk of CNS Metastasis: Population-based Demographics and Survival …

…, M Planck, A Vikström, M Johansson, A Hallqvist… - Clinical Lung Cancer, 2023 - Elsevier
Background Real-world data on demographics related to KRAS mutation subtypes are crucial
as targeted drugs against the p.G12C variant have been approved. Method We identified …