User profiles for Andreas Fritsche

Andreas Fritsche

Verified email at med.uni-tuebingen.de
Cited by 42687

Identification and characterization of metabolically benign obesity in humans

…, B Balletshofer, F Machicao, A Fritsche… - Archives of internal …, 2008 - jamanetwork.com
Background Obesity represents a risk factor for insulin resistance, type 2 diabetes mellitus,
and atherosclerosis. In addition, for any given amount of total body fat, an excess of visceral …

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

…, K Mühlenbruch, D Drogan, HG Joost, A Fritsche… - Diabetes, 2013 - Am Diabetes Assoc
Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological
pathways and help to identify individuals at risk for disease. We prospectively investigated the …

Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism

O Tschritter, A Fritsche, C Thamer, M Haap… - Diabetes, 2003 - Am Diabetes Assoc
In animals, the adipocyte-derived hormone adiponectin has been shown to improve insulin
sensitivity, a key factor in the pathogenesis of type 2 diabetes. In Pima Indians, high plasma …

α2-Heremans-Schmid Glycoprotein/ Fetuin-A Is Associated With Insulin Resistance and Fat Accumulation in the Liver in Humans

…, F Schick, SM Kröber, F Machicao, A Fritsche… - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—The α 2 -Heremans-Schmid glycoprotein (AHSG; fetuin-A in animals) impairs
insulin signaling in vitro and in rodents. Whether AHSG is associated with insulin resistance …

[HTML][HTML] Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

…, M Walker, IB Borecki, GV Dedoussis, A Fritsche… - PLoS …, 2011 - journals.plos.org
Ruth Loos and colleagues report findings from a meta-analysis of multiple studies examining
the extent to which physical activity attenuates effects of a specific gene variant, FTO, on …

An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes

…, J Spranger, C Thamer, HU Häring, A Fritsche… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—We aimed to develop a precise risk score for the screening of large
populations for individuals at high risk of developing type 2 diabetes based on noninvasive …

Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes

…, G Dailey, M Massi-Benedetti, A Fritsche… - Diabetes …, 2005 - Am Diabetes Assoc
OBJECTIVE—Insulin glargine (LANTUS) is a once-daily basal insulin analog with a smooth
24-h time-action profile that provides effective glycemic control with reduced hypoglycemia …

Association of the TG polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes

M Stumvoll, O Tschritter, A Fritsche, H Staiger… - Diabetes, 2002 - Am Diabetes Assoc
The adipocyte-derived hormone adiponectin seems to protect from insulin resistance, a key
factor in the pathogenesis of type 2 diabetes. Genome-wide scans have mapped a …

Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

…, N Stefan, A Peter, HU Häring, A Fritsche - Nature medicine, 2021 - nature.com
The state of intermediate hyperglycemia is indicative of elevated risk of developing type 2
diabetes 1 . However, the current definition of prediabetes neither reflects subphenotypes of …

Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes: a …

A Fritsche, MA Schweitzer, HU Hring… - Annals of internal …, 2003 - acpjournals.org
Background: Patients with type 2 diabetes are often treated with oral antidiabetic agents plus
a basal insulin. Objective: To investigate the efficacy and safety of glimepiride combined …