Purpose Valproic acid (VPA) is an antiepileptic agent with histone deacetylase inhibitor (HDACi)
activity shown to sensitize glioblastoma (GBM) cells to radiation in preclinical models. …

Purpose Gliomas are the most common primary tumor of the brain and are classified into
grades I‐IV of the World Health Organization (WHO), based on their invasively histological …

Radiotherapy for the treatment of cancer is undergoing an evolution, shifting to the use of
heavier ion species. For a plethora of malignancies, current radiotherapy using photons or …

Simple Summary Large-scale medical data carries significant areas of underrepresentation
and bias at all levels: clinical, biological, and management. Resulting data sets and outcome …

18 F-DCFPyL (2-(3-{1-carboxy-5-[(6- 18 F-fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic
acid), a prostate-specific membrane antigen–targeting radiotracer, has shown …

Purpose Gliomas are rapidly progressive, neurologically devastating, largely fatal brain
tumors. Magnetic resonance imaging (MRI) is a widely used technique employed in the …

This study tested the hypothesis that ABT-888 (velparib), a poly (ADP-ribose) polymerase (PARP)
inhibitor, can modulate temozolomide (TMZ) resistance in recurrent TMZ refractory …

Determining the aggressiveness of gliomas, termed grading, is a critical step toward treatment
optimization to increase the survival rate and decrease treatment toxicity for patients. …

Introduction Pseudoprogression (PsP) is a diagnostic dilemma in glioblastoma (GBM) after
chemoradiotherapy (CRT). Magnetic resonance imaging (MRI) features may fail to …

Purpose The ongoing lack of data standardization severely undermines the potential for
automated learning from the vast amount of information routinely archived in electronic health …