Design of finasteride-loaded nanoparticles for potential treatment of alopecia

…, IS Dias, N Cruz, A Rebelo, A Roberto… - Skin pharmacology and …, 2017 - karger.com
Background/Aims: Androgenetic alopecia is an extremely common dermatological disorder
affecting both men and women. Oral finasteride (FNS), a synthetic 4-aza-3-oxosteroid …

Artemia species: An important tool to screen general toxicity samples

…, EM Domínguez-Martín, A Roberto… - Current …, 2020 - ingentaconnect.com
Medicinal plants are a good source of novel therapeutic drugs, due to the phytochemicals
present. Artemia, commonly known as brine shrimp, is a tiny halophilic invertebrate belonging …

Antioxidant activity and rosmarinic acid content of ultrasound-assisted ethanolic extracts of medicinal plants

M Nicolai, P Pereira, RF Vitor, CP Reis, A Roberto… - Measurement, 2016 - Elsevier
The interest in finding natural antioxidants for use in food, drugs or cosmetic products has
increased concerning the replacement of synthetic antioxidants due to their possible …

Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies

…, P Castro, J Molpeceres, AS Viana, A Roberto… - European Polymer …, 2018 - Elsevier
Candidiasis is by far the most common fungal infection in the oral cavity and locally antifungal
drugs are generally considered the first line therapy. However, some antifungal drugs like …

Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment

…, C Rosado, AS Fernandes, A Roberto - Drug development …, 2014 - Taylor & Francis
Objective: The aim of this study was to evaluate a formulation made of poly(lactide-co-glycolide)
(PLGA) nanoparticles containing azelaic acid for potential acne treatment. Methods: …

Bioproduction of gold nanoparticles for photothermal therapy

…, P Rijo, J Molpeceres, L Ascensão, A Roberto… - Therapeutic …, 2016 - Future Science
Background: Photothermal response of plasmonic nanomaterials can be utilized for a number
of therapeutic applications such as the ablation of solid tumors. Methods & results: Gold …

[HTML][HTML] Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors

…, F Sousa, J Dinic, S Holmstedt, A Roberto… - Frontiers in …, 2020 - frontiersin.org
Cancer is among the leading causes of death worldwide. One of the most challenging obstacles
in cancer treatment is multidrug resistance (MDR). Overexpression of P-glycoprotein (P-…

Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation

…, P Rijo, M Nicolai, A Roberto… - Drug Development …, 2016 - Taylor & Francis
Context: Unsaponifiable matter (UM), a fraction of green coffee oil (GCO) contains functional
compounds responsible for desirable cosmetic properties such as UV-B absorption. …

Uptake of 7, 12‐dimethylbenz (a) anthracene and benzo (a) pyrene in melanin‐containing tissues

A Roberto, BS Larsson, H Tjälve - Pharmacology & toxicology, 1996 - Wiley Online Library
It is widely accepted that UV exposure is the main etiological factor for malignant melanoma.
Epidemiologic studies, however, have indicated that also chemical carcinogens may be a …

[HTML][HTML] Parvifloron D from Plectranthus strigosus: Cytotoxicity Screening of Plectranthus spp. Extracts

…, J Dinic, A Díaz-Lanza, C P. Reis, A Roberto… - Biomolecules, 2019 - mdpi.com
The Plectranthus genus is commonly used in traditional medicine due to its potential to treat
several illnesses, including bacterial infections and cancer. As such, aiming to screen the …