This study evaluates targeted liposomes loaded with the α-particle generator 225 Ac to
selectively kill prostate-specific membrane antigen (PSMA)–expressing cells with the aim to …

Chronic skin wounds are a common complication of diabetes. When standard wound care
fails to heal such wounds, a promising approach consists of using decellularized matrices and …

To enable selective cell-kill, we designed functionalized lipid vesicles with pH-triggered
heterogeneous membranes and encapsulated doxorubicin that exhibit tunable surface …

pH-triggered lipid-membranes designed from biophysical principles are evaluated in the
form of targeted liposomal doxorubicin with the aim to ultimately better control the growth of …

We investigated the feasibility and efficacy of a drug delivery strategy to vascularized cancer
that combines targeting selectivity with high uptake by targeted cells and high bioexposure …

Lateral lipid phase separation of titratable PS or PA lipids and their assembly in domains
induced by changes in pH are significant in liposome-based drug delivery: environmentally …

This study aims to evaluate the effect on killing efficacy of the intracellular trafficking patterns
of α-particle emitters by using different radionuclide carriers in the setting of targeted …

Background/Introduction: Lipid nanoparticles (LNPs) are one of the most clinically advanced
candidates for delivering nucleic acids to target cell populations, such as hepatocytes. Once …

The killing efficacy of doxorubicin from liposome-based delivery carriers has been shown to
correlate strongly with its intracellular trafficking and, in particular, its fast and extensive …

Lipid-based drug carriers have been used for clinically and commercially available delivery
systems due to their small size, biocompatibility, and high encapsulation efficiency. Use of …