In vivo imaging with antibodies and engineered fragments

AC Freise, AM Wu - Molecular immunology, 2015 - Elsevier
Antibodies have clearly demonstrated their utility as therapeutics, providing highly selective
and effective drugs to treat diseases in oncology, hematology, cardiology, immunology and …

[HTML][HTML] ranacapa: An R package and Shiny web app to explore environmental DNA data with exploratory statistics and interactive visualizations

…, ZJ Gold, MC Cowen, RS Meyer, AC Freise… - …, 2018 - ncbi.nlm.nih.gov
Environmental DNA (eDNA) metabarcoding is becoming a core tool in ecology and conservation
biology, and is being used in a growing number of education, biodiversity monitoring, …

ImmunoPET Imaging of Murine CD4+ T Cells Using Anti-CD4 Cys-Diabody: Effects of Protein Dose on T Cell Function and Imaging

AC Freise, KA Zettlitz, FB Salazar, X Lu… - Molecular Imaging and …, 2017 - Springer
Purpose Molecular imaging of CD4 + T cells throughout the body has implications for monitoring
autoimmune disease and immunotherapy of cancer. Given the key role of these cells in …

Immuno-PET in inflammatory bowel disease: imaging CD4-positive T cells in a murine model of colitis

AC Freise, KA Zettlitz, FB Salazar… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Inflammatory bowel diseases (IBDs) in humans are characterized in part by aberrant CD4-positive
(CD4+) T-cell responses. Currently, identification of foci of inflammation within the gut …

Instructional models for course-based research experience (CRE) teaching

…, GD Frederick, AC Freise… - CBE—Life Sciences …, 2022 - Am Soc Cell Biol
The course-based research experience (CRE) with its documented educational benefits is
increasingly being implemented in science, technology, engineering, and mathematics …

[HTML][HTML] PUMAA: a platform for accessible microbiome analysis in the undergraduate classroom

…, C Dao, AC Freise, S Mangul, C Shapiro… - Frontiers in …, 2020 - frontiersin.org
Improvements in high-throughput sequencing makes targeted amplicon analysis an ideal
method for the study of human and environmental microbiomes by undergraduates. Multiple …

[HTML][HTML] BlueFeather, the singleton that wasn't: Shared gene content analysis supports expansion of Arthrobacter phage Cluster FE

…, B Hobbs, K Hoh, E Lee, I Vuong, K Reddi, AC Freise… - Plos one, 2021 - journals.plos.org
Bacteriophages (phages) exhibit high genetic diversity, and the mosaic nature of the shared
genetic pool makes quantifying phage relatedness a shifting target. Early parameters for …

Expansion, folding, and abnormal lamination of the chick optic tectum after intraventricular injections of FGF2

LD McGowan, RA Alaama, AC Freise… - Proceedings of the …, 2012 - National Acad Sciences
Comparative research has shown that evolutionary increases in brain region volumes often
involve delays in neurogenesis. However, little is known about the influence of such …

Models of classroom assessment for course-based research experiences

…, MP Fogarty, AC Freise… - Frontiers in …, 2023 - research-repository.st-andrews.ac …
Course-based research pedagogy involves positioning students as contributors to authentic
research projects as part of an engaging educational experience that promotes their …

Exploring Genomic Conservation in Actinobacteriophages with Small Genomes

…, AS Vargas, K Reddi, JM Parker, AC Freise - bioRxiv, 2022 - biorxiv.org
Actinobacteriophages of a wide range of genome sizes continue to be isolated and
characterized, but only a handful of these have atypically small genomes, defined in this work as …