A phase I/phase II study of intravenously (IV) administered Tc 99m tilmanocept (TCT) to determine safety, tolerability, optimal clinical dose selection, and imaging …

A Kardan, A Kissling, C Hartings, R Hershey, M Blue… - 2019 - Soc Nuclear Med
89 Objectives: Activated macrophages are a critical component of the inflammatory etiology
of RA due to prolonged RA joint inflammation and destruction through the release of pro-…

Intravenous 99mTc-tilmanocept in planar and fused SPECT/CT imaging of activated macrophage infiltration in subjects with active rheumatoid arthritis

A Kardan, B Abbruzzese, A Kissling, M Haynam… - 2018 - Soc Nuclear Med
110 Objectives: Activated macrophages play a critical role in rheumatoid arthritis (RA) by
perpetuating inflammation via cytokine release and contributing to bone and cartilage …

Intravenous 99mTc-tilmanocept in Planar and Fused SPECT/CT Imaging of Activated Macrophage Infiltration in Subjects with Metastatic Liver Colorectal …

…, P Bhambhvani, J McConathy, R Paluri, A Kissling… - 2018 - Soc Nuclear Med
56 Objectives: Tumor-associatedactivated macrophages (TAMS) play a critical role in
tumorigenesis by perpetuating inflammation via cytokine release and contributing to …

Macrophage CD206 Receptor Targeting with 99m Tc-Tilmanocept Permits Specific Quantitative Diagnostic Imaging of Active Rheumatoid Arthritis (RA) and id …

…, S Behr, D Ralph, J Shuping, D Colborn, A Kissling… - 2017 - Soc Nuclear Med
303 Objectives: Macrophages play a critical role in rheumatoid arthritis (RA) disease
progression, but existing strategies for imaging disease progression in humans lack macrophage …

[PDF][PDF] Clinical Study Protocol: NAV3-21

A Kissling - classic.clinicaltrials.gov
SYNOPSIS Study title An Evaluation of the Safety of Escalating Doses of Tc 99m
Tilmanocept by Intravenous (IV) Injection and Skeletal Joint Imaging with SPECT in Subjects …

THU0540 A PHASE 2B STUDY OF INTRAVENOUSLY (IV) ADMINISTERED TC 99M TILMANOCEPT TO DETERMINE DIFFERENTIAL UPTAKE, REPRODUCIBILITY …

…, K Repp, H Shakhtra, M Goel, M Palmer, A Kissling… - 2020 - ard.bmj.com
Background: At present, there are no reliable noninvasive means to directly monitor disease
activity in RA patients. Activated macrophages are a critical component of the inflammatory …

Fisherfolk are among groups most at risk of HIV: cross-country analysis of prevalence and numbers infected

E Kissling, EH Allison, JA Seeley, S Russell… - Aids, 2005 - journals.lww.com
HIV prevalence in some fishing communities in low and middle-income countries is known
to be high relative to national average seroprevalence rates [1, 2]. Most of the studies …

[PDF][PDF] Hyphenated history: Erb-Duchenne brachial plexus palsy

C Schmitt, CT Mehlman, AL Meiss - Am J Orthop (Belle Mead NJ), 2008 - cdn.mdedge.com
Throughout history, the discoveries of their predecessors have led physicians to revolutionary
advances in the understanding and practice of medicine. The result is a plethora of …

Transactional sex in the fishing communities along Lake Victoria, Kenya: a catalyst for the spread of HIV

ZA Kwena, E Bukusi, E Omondi, M Ng'Ayo… - African journal of …, 2012 - Taylor & Francis
The study describes the nature, context and implications of a unique form of transactional
sexual relationships in the fishing communities along Lake Victoria in Kisumu County, Kenya. …

Effect of the bile acid sequestrant colesevelam on the pharmacokinetics of pioglitazone, repaglinide, estrogen estradiol, norethindrone, levothyroxine, and glyburide

…, D Swearingen, M Allison, JC Kissling… - The Journal of …, 2010 - Wiley Online Library
The purpose of this study was to assess effects of colesevelam on the pharmacokinetics of
glyburide, levothyroxine, estrogen estradiol (EE), norethindrone (NET), pioglitazone, and …