Clinical utility and user perceptions of a digital system for electronic patient-reported symptom monitoring during routine cancer care: findings from the PRO-TECT trial
…, S Henson, P Carr, B Ginos, A Deal… - JCO clinical cancer …, 2020 - ascopubs.org
PURPOSE There is increasing interest in implementing digital systems for remote monitoring
of patients’ symptoms during routine oncology practice. Information is limited about the …
of patients’ symptoms during routine oncology practice. Information is limited about the …
[HTML][HTML] Symptom monitoring with patient-reported outcomes during routine cancer treatment: a randomized controlled trial
E Basch, AM Deal, MG Kris, HI Scher… - Journal of Clinical …, 2016 - ncbi.nlm.nih.gov
Purpose There is growing interest to enhance symptom monitoring during routine cancer
care using patient-reported outcomes, but evidence of impact on clinical outcomes is limited. …
care using patient-reported outcomes, but evidence of impact on clinical outcomes is limited. …
Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment
E Basch, AM Deal, AC Dueck, HI Scher, MG Kris… - Jama, 2017 - jamanetwork.com
Methods| The study was approved by the Memorial Sloan Kettering institutional review
board and written informed consent was obtained from participants. Consecutive patients …
board and written informed consent was obtained from participants. Consecutive patients …
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
…, SU Liu, F Alimirah, K Koenig, C Le, N Mitin, AM Deal… - Cancer discovery, 2017 - AACR
Cellular senescence suppresses cancer by irreversibly arresting cell proliferation. Senescent
cells acquire a proinflammatory senescence-associated secretory phenotype. Many …
cells acquire a proinflammatory senescence-associated secretory phenotype. Many …
[HTML][HTML] Monitoring tumorigenesis and senescence in vivo with a p16INK4a-luciferase model
…, KS Clark, DB Darr, J Krishnamurthy, AM Deal… - Cell, 2013 - cell.com
Monitoring cancer and aging in vivo remains experimentally challenging. Here, we describe
a luciferase knockin mouse (p16 LUC ), which faithfully reports expression of p16 INK4a , a …
a luciferase knockin mouse (p16 LUC ), which faithfully reports expression of p16 INK4a , a …
[HTML][HTML] Cardiac toxicity after radiotherapy for stage III non–small-cell lung cancer: pooled analysis of dose-escalation trials delivering 70 to 90 Gy
K Wang, MJ Eblan, AM Deal, M Lipner… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose The significance of radiotherapy (RT)–associated cardiac injury for stage III non–small-cell
lung cancer (NSCLC) is unclear, but higher heart doses were associated with worse …
lung cancer (NSCLC) is unclear, but higher heart doses were associated with worse …
Skeletal muscle measures as predictors of toxicity, hospitalization, and survival in patients with metastatic breast cancer receiving taxane-based chemotherapy
SS Shachar, AM Deal, M Weinberg, KA Nyrop… - Clinical Cancer …, 2017 - AACR
Purpose: Severe skeletal muscle (SM) loss (sarcopenia) is associated with poor cancer
outcomes, including reduced survival and increased toxicity. This study investigates SM …
outcomes, including reduced survival and increased toxicity. This study investigates SM …
Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer
HK Sanoff, AM Deal, J Krishnamurthy… - Journal of the …, 2014 - academic.oup.com
Background Senescent cells, which express p16 INK4a , accumulate with aging and contribute
to age-related pathology. To understand whether cytotoxic agents promote molecular …
to age-related pathology. To understand whether cytotoxic agents promote molecular …
Geriatric assessment-identified deficits in older cancer patients with normal performance status
TA Jolly, AM Deal, KA Nyrop, GR Williams… - The …, 2015 - academic.oup.com
Background. We investigated whether a brief geriatric assessment (GA) would identify important
patient deficits that could affect treatment tolerance and care outcomes within a sample …
patient deficits that could affect treatment tolerance and care outcomes within a sample …
The prognostic contribution of clinical breast cancer subtype, age, and race among patients with breast cancer brain metastases
BACKGROUND: Brain metastases (BM) arising from triple‐negative breast cancer (TNBC)
portend a poor prognosis. TNBC is more common in premenopausal and African‐American (…
portend a poor prognosis. TNBC is more common in premenopausal and African‐American (…