Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and
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MRI-based measurements of surface cortical thickness (SCT) have become a sensitive tool
to quantify changes in cortical morphology. When comparing SCT to histological cortical …

Radiolabeled peptides for tumor imaging with PET that can be produced with kits are currently
in the spotlight of radiopharmacy and nuclear medicine. The diagnosis of neuroendocrine …

Changes in expression and dysfunctional signaling of TrkA/B/C receptors and oncogenic
Trk fusion proteins are found in neurological diseases and cancers. Here, we describe the …

Here we present a procedure to label peptides with the positron-emitting radioisotope
fluorine-18 (18 F) using the silicon-fluoride acceptor (SiFA) labeling methodology. Positron …

Imaging biomarkers are frequently proposed as endpoints for clinical trials targeting brain
amyloidosis in Alzheimer9s disease (AD); however, the specific impact of amyloid-β (Aβ) …

Background. Over the recent years, radiopharmaceutical chemistry has experienced a wide
variety of innovative pushes towards finding both novel and unconventional radiochemical …

N-Succinimidyl 3-(di-tert-butyl[ 18 F]fluorosilyl)benzoate ([ 18 F]SiFB), a novel synthon for
one-step labeling of proteins, was synthesized via a simple 18 F– 19 F isotopic exchange. A …

Silicon-[ 18 F]fluorine (Si- 18 F) radiochemistry has recently emerged alongside other
unconventional approaches such as aluminum- 18 F and boron- 18 F based labeling strategies, …

N-Terminally azido-modified peptides were labeled with the novel prosthetic labeling
synthon [ 18 F]azadibenzocyclooctyne ([ 18 F]ADIBO) using copper-free azide-alkyne [3+2]-dipolar …