Recent studies provide increasing evidence that postnatal neovascularization involves bone
marrow–derived circulating endothelial progenitor cells (EPCs). The regulation of EPCs in …

Pancreatic adenocarcinoma is currently the fourth leading cause for cancer-related mortality.
Stem cells have been implicated in pancreatic tumor growth, but the specific role of these …

Background— Experimental studies suggest that transplantation of blood-derived or bone
marrow–derived progenitor cells beneficially affects postinfarction remodeling. The safety and …

Endothelial nitric oxide synthase (eNOS) is essential for neovascularization. Here we show
that the impaired neovascularization in mice lacking eNOS is related to a defect in progenitor …

HMG-CoA reductase inhibitors (statins) have been developed as lipid-lowering drugs and
are well established to reduce morbidity and mortality from coronary artery disease. Here we …

Background—Therapeutic neovascularization may constitute an important strategy to salvage
tissue from critical ischemia. Circulating bone marrow–derived endothelial progenitor cells …

Increasing evidence suggests that postnatal neovascularization involves the recruitment of
circulating endothelial progenitor cells (EPCs). Hematopoietic and endothelial cell lineages …

Circulating endothelial progenitor cells (EPC) are incorporated into newly formed capillaries,
enhance neovascularization after hind limb ischemia and improve cardiac function after …

Background— Further to promoting angiogenesis, cell therapy may be an approach for
cardiac regeneration. Recent studies suggest that progenitor cells can transdifferentiate into …

Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel
option for improving neovascularization and cardiac function in ischemic heart disease. …