Radiohybrid ligands: a novel tracer concept exemplified by 18F-or 68Ga-labeled rhPSMA inhibitors
A Wurzer, D Di Carlo, A Schmidt, R Beck… - Journal of Nuclear …, 2020 - Soc Nuclear Med
When we critically assess the reason for the current dominance of 68 Ga-labeled peptides
and peptide-like ligands in radiopharmacy and nuclear medicine, we have to conclude that …
and peptide-like ligands in radiopharmacy and nuclear medicine, we have to conclude that …
18F-rhPSMA-7 PET for the detection of biochemical recurrence of prostate cancer after radical prostatectomy
M Eiber, M Kroenke, A Wurzer, L Ulbrich… - Journal of Nuclear …, 2020 - Soc Nuclear Med
18 F-labeled prostate-specific membrane antigen (PSMA) PET tracers are increasingly used
in preference to 68 Ga-PSMA-11 for restaging biochemical recurrence (BCR) of prostate …
in preference to 68 Ga-PSMA-11 for restaging biochemical recurrence (BCR) of prostate …
Selective targeting of integrin αvβ8 by a highly active cyclic peptide
…, UK Marelli, J Notni, A Wurzer… - Journal of medicinal …, 2019 - ACS Publications
Integrins play important roles in physiological and pathophysiological processes. Among
the RGD-recognizing integrin subtypes, the αvβ8 receptor is emerging as an attractive target …
the RGD-recognizing integrin subtypes, the αvβ8 receptor is emerging as an attractive target …
Microscopic mechanism of ultrafast excited-state intramolecular proton transfer: A 30-fs study of 2-(2 '-hydroxyphenyl) benzothiazole
S Lochbrunner, AJ Wurzer, E Riedle - The Journal of Physical …, 2003 - ACS Publications
A detailed analysis of the excited-state intramolecular proton transfer (ESIPT) of 2-(2‘-hydroxyphenyl)benzothiazole
and the associated wave packet motion is presented. It is based on …
and the associated wave packet motion is presented. It is based on …
Synthesis and preclinical characterization of the PSMA-targeted hybrid tracer PSMA-I&F for nuclear and fluorescence imaging of prostate cancer
M Schottelius, A Wurzer, K Wissmiller… - Journal of Nuclear …, 2019 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA)–targeted radiotracers 68 Ga/ 177 Lu-PSMA-I&T
and 99m Tc-PSMA-I&S (for imaging and surgery) are currently successfully used for …
and 99m Tc-PSMA-I&S (for imaging and surgery) are currently successfully used for …
[PDF][PDF] Matched-pair comparison of 68Ga-PSMA-11 and 18F-rhPSMA-7 PET/CT in patients with primary and biochemical recurrence of prostate cancer: Frequency of …
…, L Mirzoyan, T Horn, JC Peeken, A Wurzer… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Radiohybrid prostate-specific membrane antigen (rhPSMA) ligands are a new class of prostate
cancer theranostic agents. 18F-rhPSMA-7 offers the advantages of 18F labeling and low …
cancer theranostic agents. 18F-rhPSMA-7 offers the advantages of 18F labeling and low …
[HTML][HTML] Preclinical comparison of four [18F, natGa]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics
A Wurzer, M Parzinger, M Konrad, R Beck, T Günther… - EJNMMI research, 2020 - Springer
Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted
radiopharmaceuticals, can be labeled either with [ 18 F]fluorine via isotopic …
radiopharmaceuticals, can be labeled either with [ 18 F]fluorine via isotopic …
Quantitative and qualitative analyses of biodistribution and PET image quality of a novel radiohybrid PSMA, 18F-rhPSMA-7, in patients with prostate cancer
SW Oh, A Wurzer, EJ Teoh, S Oh… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Radiohybrid PSMA (rhPSMA) ligands, a new class of theranostic prostate-specific membrane
antigen (PSMA)–targeting agents, feature fast 18 F synthesis and utility for labeling with …
antigen (PSMA)–targeting agents, feature fast 18 F synthesis and utility for labeling with …
Molar activity of Ga-68 labeled PSMA inhibitor conjugates determines PET imaging results
A Wurzer, J Pollmann, A Schmidt, D Reich… - Molecular …, 2018 - ACS Publications
Radiopharmaceuticals targeting the enzyme prostate-specific membrane antigen (PSMA;
synonyms: glutamate carboxypeptidase II, NAALADase; EC 3.4.17.21) have recently emerged …
synonyms: glutamate carboxypeptidase II, NAALADase; EC 3.4.17.21) have recently emerged …
Synthesis and preclinical evaluation of 177Lu-labeled radiohybrid PSMA ligands for endoradiotherapy of prostate cancer
A Wurzer, JP Kunert, S Fischer, V Felber… - Journal of Nuclear …, 2022 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA)–targeted radiohybrid (rh) ligand [ 177 Lu]Lu-rhPSMA-7.3
has recently been assessed in a pretherapeutic dosimetry study on prostate …
has recently been assessed in a pretherapeutic dosimetry study on prostate …