User profiles for Alexander Rühle

Alexander Rühle

University Medical Center Leipzig
Verified email at uniklinik-freiburg.de
Cited by 904

Finanzielle Toxizität bei Krebspatient* innen unter Strahlentherapie

A Fabian, A Rühle, JN Becker, E Bockelmann… - Forum, 2022 - Springer
Hintergrund Krebspatient* innen können erheblichen finanziellen Belastungen ausgesetzt
sein. Vor diesem Hintergrund hat sich der Begriff der finanziellen Toxizität im Rahmen der …

[HTML][HTML] Radiotherapy for geriatric head-and-neck cancer patients: what is the value of standard treatment in the elderly?

E Haehl, A Rühle, H David, T Kalckreuth, T Sprave… - Radiation …, 2020 - Springer
Background Head-and-neck squamous cell carcinoma (HNSCC) is one of the most common
malignancies globally, and the number of elderly patients diagnosed with HNSCC is …

[HTML][HTML] De-escalation strategies of (chemo) radiation for head-and-neck squamous cell cancers—HPV and beyond

A Rühle, AL Grosu, NH Nicolay - Cancers, 2021 - mdpi.com
Simple Summary HPV-related oropharyngeal squamous cell carcinoma patients have a
very good prognosis but are often suffering from long-term treatment-induced toxicities. …

To divide or not to divide? The impact of partitioned pricing on the informational and sacrifice effects of price

F Völckner, A Rühle, M Spann - Marketing Letters, 2012 - Springer
Firms often partition a product’s price into two mandatory parts (eg, the base price of a mail-order
DVD and the surcharge for shipping and handling) instead of charging one all-…

[HTML][HTML] Real-world prospective analysis of treatment patterns in durvalumab maintenance after chemoradiotherapy in unresectable, locally advanced NSCLC patients

J Taugner, L Käsmann, C Eze, A Rühle… - Investigational new …, 2021 - Springer
The aim of this prospective study is to evaluate the clinical use and real-world efficacy of
durvalumab maintenance treatment after chemoradiotherapy (CRT) in unresectable stage, …

[HTML][HTML] Is there a role for stereotactic radiotherapy in the treatment of renal cell carcinoma?

A Rühle, N Andratschke, S Siva… - Clinical and translational …, 2019 - Elsevier
Renal cell carcinoma (RCC) has traditionally been regarded as radioresistant tumor based
on preclinical data and negative clinical trials using conventional fractionated radiotherapy. …

[HTML][HTML] Mesenchymal stem cells are sensitive to bleomycin treatment

NH Nicolay, A Rühle, RL Perez, T Trinh, S Sisombath… - Scientific reports, 2016 - nature.com
Mesenchymal stem cells (MSCs) have been shown to attenuate pulmonary damage induced
by bleomycin-based anticancer treatments, but the influence of bleomycin on the stem cells …

The current understanding of mesenchymal stem cells as potential attenuators of chemotherapy‐induced toxicity

A Rühle, PE Huber, R Saffrich… - … journal of cancer, 2018 - Wiley Online Library
Chemotherapeutic agents are part of the standard treatment algorithms for many malignancies;
however, their application and dosage are limited by their toxic effects to normal tissues. …

The utility of multiparametric MRI to characterize hypoxic tumor subvolumes in comparison to FMISO PET/CT. Consequences for diagnosis and chemoradiation …

…, J Ruf, L Bielak, L Majerus, A Rühle… - Radiotherapy and …, 2020 - Elsevier
Background and Purpose Hypoxia is an essential metabolic marker that determines chemo-
and radiation resistance in head-and-neck squamous cell carcinoma (HNSCC) patients. …

[HTML][HTML] Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin

NH Nicolay, RL Perez, A Rühle, T Trinh, S Sisombath… - Scientific reports, 2016 - nature.com
Mesenchymal stem cells (MSCs) aid the regeneration of tissues damaged by treatment with
cisplatin. However, the effects of this cytotoxic drug on the stem cells have been largely …