In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …

Brain injury induces a peripheral acute cytokine response that directs the transmigration of
leukocytes into the brain. Because this brain-to-peripheral immune communication affects …

It remains unclear how different translocator protein (TSPO) ligands reflect the spatial extent
of astrocyte or microglial activation in various neuroinflammatory conditions. Here, we use a …

It is well established that gut microbes and their metabolic products regulate host metabolism.
The interactions between the host and its gut microbiota are highly dynamic and complex. …

Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain
injury (TBI). Associations between this and systemic metabolism and their potential prognostic …

… Alex M Dickens … Alex M. Dickens main research interest is in the use of metabolomics to
understand neurological diseases. As such, he has developed both targeted and untargeted …

The widespread use of combinational antiretroviral therapies (cART) in developed countries
has changed the course of Human Immunodeficiency Virus (HIV) infection from an almost …

Objective: We tested whether it is possible to differentiate relapsing-remitting (RR) from
secondary progressive (SP) disease stages in patients with multiple sclerosis (MS) using a …

Background A key clinical challenge in the management of individuals at clinical high risk
for psychosis (CHR) is that it is difficult to predict their future clinical outcomes. Here, we …

Deposition of amyloid-β plaques is increased in the brains of HIV-infected individuals, and
the HIV transactivator of transcription (Tat) protein affects amyloidogenesis through several …