Restoration of brain circulation and cellular functions hours post-mortem
The brains of humans and other mammals are highly vulnerable to interruptions in blood
flow and decreases in oxygen levels. Here we describe the restoration and maintenance of …
flow and decreases in oxygen levels. Here we describe the restoration and maintenance of …
[HTML][HTML] Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction
…, JA Madri, BL Zaret, AJ Sinusas - The Journal of …, 2004 - Am Soc Clin Investig
Noninvasive imaging strategies will be critical for defining the temporal characteristics of
angiogenesis and assessing efficacy of angiogenic therapies. The αvβ3 integrin is expressed in …
angiogenesis and assessing efficacy of angiogenic therapies. The αvβ3 integrin is expressed in …
[HTML][HTML] Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel
…, R Sawh-Martinez, JK Harrington, A Sinusas… - The FASEB …, 2011 - ncbi.nlm.nih.gov
We developed a tissue-engineered vascular graft composed of biodegradable scaffold
seeded with autologous bone marrow-derived mononuclear cells (BMMCs) that is currently in …
seeded with autologous bone marrow-derived mononuclear cells (BMMCs) that is currently in …
Estimation of 3-D left ventricular deformation from medical images using biomechanical models
X Papademetris, AJ Sinusas, DP Dione… - IEEE transactions on …, 2002 - ieeexplore.ieee.org
The quantitative estimation of regional cardiac deformation from three-dimensional (3-D)
image sequences has important clinical implications for the assessment of viability in the heart …
image sequences has important clinical implications for the assessment of viability in the heart …
Deep learning for prediction of obstructive disease from fast myocardial perfusion SPECT: a multicenter study
…, MB Fish, TD Ruddy, P Kaufmann, AJ Sinusas… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives : The study evaluated the automatic prediction of obstructive disease from myocardial
perfusion imaging (MPI) by deep learning as compared with total perfusion deficit (TPD)…
perfusion imaging (MPI) by deep learning as compared with total perfusion deficit (TPD)…
Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo
…, X Hu, M Caplan, J Ren, GI Shulman, AJ Sinusas - Circulation, 1997 - Am Heart Assoc
Background Myocardial ischemia increases heart glucose utilization in vivo. However, whether
low-flow ischemia leads to the translocation of glucose transporter (GLUT)-4 and/or GLUT…
low-flow ischemia leads to the translocation of glucose transporter (GLUT)-4 and/or GLUT…
Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction
…, C MacGillivray, RT Lee, AJ Sinusas… - American Journal …, 2006 - journals.physiology.org
Matrix metalloproteinases (MMPs) are postulated to be necessary for neovascularization
during wound healing. MMP-9 deletion alters remodeling postmyocardial infarction (post-MI), …
during wound healing. MMP-9 deletion alters remodeling postmyocardial infarction (post-MI), …
Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model
…, TL Mirensky, T Yi, TF Hazlett, G Tellides, AJ Sinusas… - Biomaterials, 2008 - Elsevier
The development of neotissue in tissue engineered vascular grafts remains poorly understood.
Advances in mouse genetic models have been highly informative in the study of vascular …
Advances in mouse genetic models have been highly informative in the study of vascular …
Estimation of 3D left ventricular deformation from echocardiography
X Papademetris, AJ Sinusas, DP Dione… - Medical image …, 2001 - Elsevier
The quantitative estimation of regional cardiac deformation from 3D image sequences has
important clinical implications for the assessment of viability in the heart wall. Such estimates …
important clinical implications for the assessment of viability in the heart wall. Such estimates …
Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling
…, S Robinson, DS Edwards, AJ Sinusas - Circulation, 2005 - Am Heart Assoc
… Drs Spinale and Sinusas have sponsored research agreements with Bristol-Myers Squibb
Medical Imaging, North Billerica, Mass. Drs Azure, Yalamanchili, Liu, Cheesman, Robinson, …
Medical Imaging, North Billerica, Mass. Drs Azure, Yalamanchili, Liu, Cheesman, Robinson, …