Phosphatidylinositol 3-kinases (PI3Ks) and mammalian target of rapamycin (mTOR) play a
role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Omipalisib (GSK2126458) is a …

Purpose There is a lack of prognostic biomarkers in idiopathic pulmonary fibrosis (IPF) patients.
The objective of this study is to investigate the potential of 18 F-FDG-PET/ CT to predict …

Planar 2D x-ray mammography is generally accepted as the preferred screening technique
used for breast cancer detection. Recently, digital breast tomosynthesis (DBT) has been …

PET with 18 F-FDG has been increasingly applied, predominantly in the research setting, to
study drug effects and pulmonary biology and to monitor disease progression and treatment …

… Porter, Thida Win, Kjell Erlandsson, Francesco Fraioli, Alaleh Rashidnasab, Beverley
Holman, Balaji Ganeshan, Nicholas J. Screaton, Toby M. Maher, Raymond Endozo, John …

This work presents a joint activity/attenuation reconstruction method in SPECT, based on
the maximisation of the scatter and non-scatter data joint log-likelihood. The activity image is …

This work compares the visibility of spheres and simulated masses in 2D-mammography
and tomosynthesis systems using human observer studies. Performing comparison studies …

Virtual clinical trials are a promising new approach increasingly used for the evaluation and
comparison of breast imaging modalities. A key component in such an assessment …

Digital breast tomosynthesis (DBT) is suggested to have superior performance compared to
2D mammography in terms of cancer visibility, especially in the case of dense breasts. …

The aim of the present work was to develop a method for simulating breast lesions in digital
mammographic images. Based on the visual appearance of real masses, three dimensional …