User profiles for Alain C. Colige
Alain ColigeLaboratory of Connective Tissue Biology, GIGA, University of Liege, Belgium Verified email at uliege.be Cited by 9682 |
[HTML][HTML] Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the …
BV Nusgens, AC Colige, CA Lambert… - Journal of Investigative …, 2001 - Elsevier
Ascorbic acid (vitamin C) is a cofactor required for the function of several hydroxylases and
monooxygenases. It is not synthesized in humans and some other animal species and has to …
monooxygenases. It is not synthesized in humans and some other animal species and has to …
[HTML][HTML] Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated …
The extracellular pH (pHe) of tumor tissues is often acidic, which can induce the expression
of several proteins. We previously showed that production of matrix metalloproteinase-9 (…
of several proteins. We previously showed that production of matrix metalloproteinase-9 (…
[HTML][HTML] Effects of mild cold shock (25 C) followed by warming up at 37 C on the cellular stress response
T Neutelings, CA Lambert, BV Nusgens, AC Colige - PloS one, 2013 - journals.plos.org
Temperature variations in cells, tissues and organs may occur in a number of circumstances.
We report here that reducing temperature of cells in culture to 25C for 5 days followed by a …
We report here that reducing temperature of cells in culture to 25C for 5 days followed by a …
18F-FDG uptake assessed by PET/CT in abdominal aortic aneurysms is associated with cellular and molecular alterations prefacing wall deterioration and rupture
…, P Delvenne, JB Michel, AC Colige… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Rupture of abdominal aortic aneurysms (AAAs) leads to a significant morbidity and mortality
in aging populations, and its prediction would be most beneficial to public health. Spots …
in aging populations, and its prediction would be most beneficial to public health. Spots …
Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen …
Mutations in ADAMTS2, a procollagen amino-propeptidase, cause severe skin fragility,
designated as dermatosparaxis in animals, and a subtype of the Ehlers-Danlos syndrome (…
designated as dermatosparaxis in animals, and a subtype of the Ehlers-Danlos syndrome (…
Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents
P Mineur, AC Colige, CF Deroanne, J Dubail… - The Journal of cell …, 2007 - rupress.org
Ultraviolet B and genotoxic drugs induce the expression of a vascular endothelial growth factor
A (VEGF-A) splice variant (VEGF111) encoded by exons 1–4 and 8 in many cultured cells…
A (VEGF-A) splice variant (VEGF111) encoded by exons 1–4 and 8 in many cultured cells…
[HTML][HTML] Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment
Lipogenesis inhibition was reported to induce apoptosis and repress proliferation of cancer
cells while barely affecting normal cells. Lipins exhibit dual function as enzymes catalyzing …
cells while barely affecting normal cells. Lipins exhibit dual function as enzymes catalyzing …
[HTML][HTML] Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression
…, B Nusgens, V Castronovo, M Thiry, AC Colige… - Scientific reports, 2018 - nature.com
Propranolol, a widely used non-selective beta-adrenergic receptor blocker, was recently
shown to display anticancer properties. Its potential to synergize with certain drugs has been …
shown to display anticancer properties. Its potential to synergize with certain drugs has been …
Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension
CA Lambert, AC Colige, C Munaut, CM Lapière… - Matrix Biology, 2001 - Elsevier
The aim of the work was to analyze, on a comparative basis, the signaling pathways operating
in the regulation of a panel of matrix metalloproteinases (MMP) expressed by human …
in the regulation of a panel of matrix metalloproteinases (MMP) expressed by human …
Metallothionein-dependent up-regulation of TGF-β2 participates in the remodelling of the myxomatous mitral valve
…, MA Radermecker, AC Colige - Cardiovascular …, 2012 - academic.oup.com
Aims Although an excessive extracellular matrix remodelling has been well described in
myxomatous mitral valve (MMV), the underlying pathogenic mechanisms remain largely …
myxomatous mitral valve (MMV), the underlying pathogenic mechanisms remain largely …