[PDF][PDF] Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase
S Jeger, K Zimmermann, A Blanc, J Grünberg… - Angew Chem Int Ed …, 2010 - academia.edu
The therapeutic efficacy of antibodies can be substantially enhanced by conjugation of cytotoxic
compounds such as chemotherapeutics and particle-emitting radionuclides.[1] Intuitively …
compounds such as chemotherapeutics and particle-emitting radionuclides.[1] Intuitively …
Future prospects for SPECT imaging using the radiolanthanide terbium-155—production and preclinical evaluation in tumor-bearing mice
…, H Dorrer, J Reber, S Haller, S Cohrs, A Blanc… - Nuclear medicine and …, 2014 - Elsevier
Introduction We assessed the suitability of the radiolanthanide 155 Tb (t 1/2 = 5.32 days, E γ
= 87 keV (32%), 105 keV (25%)) in combination with variable tumor targeted biomolecules …
= 87 keV (32%), 105 keV (25%)) in combination with variable tumor targeted biomolecules …
High‐resolution SPECT imaging of stimuli‐responsive soft microrobots
Untethered small‐scale robots have great potential for biomedical applications. However,
critical barriers to effective translation of these miniaturized machines into clinical practice exist…
critical barriers to effective translation of these miniaturized machines into clinical practice exist…
Preclinical evaluation of a new, stabilized neurotensin (8–13) pseudopeptide radiolabeled with 99mTc
…, P Bläuenstein, M Bruehlmeier, A Blanc… - Journal of Nuclear …, 2002 - Soc Nuclear Med
The rapid degradation of neurotensin (NT) limits its clinical use in cancer imaging and therapy.
Thus, a new NT(8–13) pseudopeptide, NT-VIII, was synthesized. Some changes were …
Thus, a new NT(8–13) pseudopeptide, NT-VIII, was synthesized. Some changes were …
Chemical and biological characterization of new Re (CO) 3/[99mTc](CO) 3 bombesin analogues
…, M Zwimpfer, IU Khan, V Maes, A Blanc… - Nuclear medicine and …, 2007 - Elsevier
INTRODUCTION: Bombesin, a neuropeptide with potential for breast and prostate tumor
targeting, is rapidly metabolized in vivo, and as a result, uptake in tumor xenografts in mice is …
targeting, is rapidly metabolized in vivo, and as a result, uptake in tumor xenografts in mice is …
Dual, Site‐Specific Modification of Antibodies by Using Solid‐Phase Immobilized Microbial Transglutaminase
…, D Messmer, A Ritler, A Küchler, A Blanc… - …, 2017 - Wiley Online Library
Microbial transglutaminase (MTG) was stably solid‐phase immobilized on glass microbeads
by using a second‐generation dendronized polymer. Immobilized MTG enabled the …
by using a second‐generation dendronized polymer. Immobilized MTG enabled the …
A stable neurotensin-based radiopharmaceutical for targeted imaging and therapy of neurotensin receptor-positive tumours
E García-Garayoa, P Bläuenstein, A Blanc… - European journal of …, 2009 - Springer
Purpose Neurotensin (NT) and its high affinity receptor (NTR1) are involved in several
neoplastic processes. Thus, NT-based radiopharmaceuticals are potential tracers for targeted …
neoplastic processes. Thus, NT-based radiopharmaceuticals are potential tracers for targeted …
Stabilization of neurotensin analogues: effect on peptide catabolism, biodistribution and tumor binding
M Bruehlmeier, EG Garayoa, A Blanc, B Holzer… - Nuclear medicine and …, 2002 - Elsevier
Neurotensin (NT) receptors in pancreatic and other neuroendocrine tumors are promising
targets for imaging and therapeutic purposes. Here, we report on the effect of distinct changes …
targets for imaging and therapeutic purposes. Here, we report on the effect of distinct changes …
[HTML][HTML] Evaluation of Actinium-225 Labeled Minigastrin Analogue [225Ac]Ac-DOTA-PP-F11N for Targeted Alpha Particle Therapy
The overexpression of cholecystokinin B receptor (CCKBR) in human cancers led to the
development of radiolabeled minigastrin analogues for targeted radionuclide therapy, which …
development of radiolabeled minigastrin analogues for targeted radionuclide therapy, which …
[HTML][HTML] Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering
PS Lienemann, S Metzger, AS Kiveliö, A Blanc… - Scientific reports, 2015 - nature.com
Over the last decades, great strides were made in the development of novel implants for the
treatment of bone defects. The increasing versatility and complexity of these implant designs …
treatment of bone defects. The increasing versatility and complexity of these implant designs …