Results: After administrationof 166Ho-chitosancomplex, the radio active concentrations in
blood were low, and cumulative urinary and fecal excretions over a period of 0-72 hr were 0.53…

MKT-077 (1-ethyl-2-{[3-ethyl-5-(3-methylbenzothiazolin-2-yliden)]-4-oxothiazolidin-2-ylidenemethyl}
pyridinium chloride), a novel rhodacyanine dye in phase I/II clinical trials, may …

Purpose The objective of this study was to determine the fate of the 166 Ho-chitosan
complex (DW-166HC) in rats by examining its absorption, distribution and excretion after …

Developmental toxicity studies were conducted in rats and rabbits with a human G-CSF
derivative (NTG). As reported for G-CSF, increases in abortions and fetal mortality were …

Background/Aims/Methods: The distribution characteristics of a human colon carcinoma cell
line, KM12-HX cells, were examined. After intraportal vein (ipv) or intravenous (iv) injection …

The aim of this study was to determine the metabolizing activities in the liver of patients with
hepatocellular carcinoma (HCC). Thin-layer chromatography autoradioluminography was …

Autoradiographic data of distinctive tissue distributions of 14 C atoms obtained by labeling at
two different positions of a new drug suggest the metabolic fates of each labeled compound …

Evidence is presented to elucidate whether or not quantitative analysis of autoradiographs
can be obtained with a 14 C-labelled compound by the use of a new type of radiosensor …

By the use of acetylsalicylic acid (aspirin) 14 C-labelled in either the acetyl or the carboxyl
group, the metabolic pathway and the degree of degradation of the substance were studied. …

In pharmacokinetic studies, ordinary methods of identifying or quantitatively measuring
metabolites have been complicated and become difficult to handle. Here, a novel TLC-…