Maturation of Human Dendritic Cells by Cell Wall Skeleton of Mycobacterium bovis Bacillus Calmette-Guérin: Involvement of Toll-Like Receptors

…, O Takeuchi, S Akira, I Azuma, A Hayashi… - Infection and …, 2000 - Am Soc Microbiol
The constituents of mycobacteria are an effective immune adjuvant, as observed with
complete Freund's adjuvant. In this study, we demonstrated that the cell wall skeleton of …

Analysis of 1,992 patients with anorectal malformations over the past two decades in Japan

M Endo, A Hayashi, M Ishihara, M Maie… - Journal of pediatric …, 1999 - Elsevier
Background/Purpose: This report describes the results of a group study of the Japanese Study
Group of Anorectal Anomolies (JSGA) to determine the relative incidence of specific types …

[HTML][HTML] A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

…, M Yasukawa, Y Kassai, A Hayashi… - Nature …, 2021 - nature.com
Clinical successes demonstrated by chimeric antigen receptor T-cell immunotherapy have
facilitated further development of T-cell immunotherapy against wide variety of diseases. One …

Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins

T Nakanishi, J Kunisawa, A Hayashi, Y Tsutsumi… - Journal of controlled …, 1999 - Elsevier
In order to design an optimized liposome immunoadjuvant for inducing cell-mediated immune
response against soluble proteinaceous antigens, we investigated the effect of liposomal …

An enzymic reduction system for metmyoglobin and methemoglobin, and its application to functional studies of oxygen carriers

A Hayashi, T Suzuki, M Shin - Biochimica et Biophysica Acta (BBA)-Protein …, 1973 - Elsevier
Enzymic reductions of oxygen-carrying hemeproteins were studied. The standard components
for the reductions were an NADPH-generating system (NADP, glucose 6-phosphate and …

[HTML][HTML] Regulation of autophagy and its associated cell death by “sphingolipid rheostat”: reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian …

…, M Hashimoto-Nishimura, S Asano, A Hayashi… - Journal of Biological …, 2012 - ASBMB
The role of "sphingolipid rheostat" by ceramide and sphingosine 1-phosphate (S1P) in the
regulation of autophagy remains unclear. In human leukemia HL-60 cells, amino acid …

[PDF][PDF] Enhancing T cell receptor stability in rejuvenated iPSC-derived T cells improves their use in cancer immunotherapy

…, H Miyoshi, M Nakanishi, A Watanabe, A Hayashi… - Cell Stem Cell, 2018 - cell.com
Limited T cell availability and proliferative exhaustion present major barriers to successful T
cell-based immunotherapies and may potentially be overcome through the use of "…

Positively charged liposome functions as an efficient immunoadjuvant in inducing immune responses to soluble proteins

T Nakanishi, J Kunisawa, A Hayashi, Y Tsutsumi… - Biochemical and …, 1997 - Elsevier
To design an optimum liposome immunoadjuvant for soluble protein antigens, we investigated
the relationship between liposomal surface charge and adjuvant action. Positively …

The epithelial-mesenchymal interface of the male rat Mullerian duct: loss of basement membrane integrity and ductal regression

RL Trelstad, A Hayashi, K Hayashi, PK Donahoe - Developmental biology, 1982 - Elsevier
Regression of the Mullerian duct in the male rat embryo is accompanied by degeneration
and phagocytosis of epithelial and mesenchymal cells, removal of the ductal basement …

Gelation of gelatin solution

A Hayashi, SC Oh - Agricultural and Biological Chemistry, 1983 - Taylor & Francis
In order to study the gelling mechanism of gelatin, the phase diagram for a diluted gelatin
solution was investigated. Phase boundary curves were obtained by measuring the fluorescent …