User profiles for Abigail Besemer

Abigail Besemer

Assistant Professor, Department of Human Oncology, University of Wisconsin
Verified email at wisc.edu
Cited by 289

Development and validation of RAPID: a patient-specific Monte Carlo three-dimensional internal dosimetry platform

AE Besemer, YM Yang, JJ Grudzinski… - Cancer biotherapy & …, 2018 - liebertpub.com
This work describes the development and validation of a patient-specific Monte Carlo internal
dosimetry platform called RAPID (Radiopharmaceutical Assessment Platform for Internal …

Minimum dose rate estimation for pulsed FLASH radiotherapy: A dimensional analysis

…, Q Fan, Y Yan, S Wang, Y Lei, A Besemer… - Medical …, 2020 - Wiley Online Library
Purpose/objectives To provide an order of magnitude estimate of the minimum dose rate ( )
required by pulsed ultra‐high dose rate radiotherapy (FLASH RT) using dimensional analysis…

The clinical impact of uncertainties in the mean excitation energy of human tissues during proton therapy

A Besemer, H Paganetti… - Physics in Medicine & …, 2013 - iopscience.iop.org
Uncertainties in the estimated mean excitation energies (I-values) needed for calculating
proton stopping powers can be in the order of 10–15%, which introduces a fundamental …

Preclinical pharmacokinetics and dosimetry studies of 124I/131I-CLR1404 for treatment of pediatric solid tumors in murine xenograft models

…, J Grudzinski, DC Baiu, A Besemer… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Cancer is the second leading cause of death for children between the ages of 5 and 14 y. For
children diagnosed with metastatic or recurrent solid tumors, for which the utility of external-…

Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer model systems

…, J Saker, EA Armstrong, A Besemer… - Radiotherapy and …, 2015 - Elsevier
Background and purpose CLR1404 is a phospholipid ether that exhibits selective uptake
and retention in malignant tissues. Radiolabeled CLR1404 enables tumor-specific positron-…

Impact of PET and MRI threshold-based tumor volume segmentation on patient-specific targeted radionuclide therapy dosimetry using CLR1404

AE Besemer, B Titz, JJ Grudzinski… - Physics in Medicine …, 2017 - iopscience.iop.org
Variations in tumor volume segmentation methods in targeted radionuclide therapy (TRT)
may lead to dosimetric uncertainties. This work investigates the impact of PET and MRI …

Radiation treatment planning and delivery strategies for a pregnant brain tumor patient

…, RA Bayliss, AE Besemer… - Journal of applied …, 2018 - Wiley Online Library
The management of a pregnant patient in radiation oncology is an infrequent event requiring
careful consideration by both the physician and physicist. The aim of this manuscript was to …

Pretreatment CLR 124 positron emission tomography accurately predicts CLR 131 three-dimensional dosimetry in a triple-negative breast cancer patient

AE Besemer, JJ Grudzinski, JP Weichert… - Cancer Biotherapy & …, 2019 - liebertpub.com
Introduction: CLR1404 is a theranostic molecular agent that can be radiolabeled with 124 I (CLR
124) for positron emission tomography (PET) imaging, or 131 I (CLR 131) for single-…

Implementation of a real‐time, ultrasound‐guided prostate HDR brachytherapy program

…, D Dunkerley, RT Flynn, AE Besemer… - Journal of applied …, 2021 - Wiley Online Library
This work presents a comprehensive commissioning and workflow development process of
a real‐time, ultrasound (US) image‐guided treatment planning system (TPS), a stepper and …

Diagnosing atmospheric communication of a sealed monitor chamber

…, M Belanger, A Besemer… - Journal of applied …, 2020 - Wiley Online Library
Daily output variations of up to ±2% were observed for a protracted time on a Varian
TrueBeam® STx; these output variations were hypothesized to be the result of atmospheric …