We conducted a prospective study to update our knowledge of fever of unknown origin (FUO)
and to explore the utility of a structured diagnostic protocol. From December 2003 to July …

Background Self‐monitoring of blood glucose is essential to optimise glycaemic control in
type 1 diabetes mellitus. Continuous glucose monitoring (CGM) systems measure interstitial …

Purpose Since 18 F-fluorodeoxyglucose (FDG) accumulates in neoplastic cells and in activated
inflammatory cells, positron emission tomography (PET) with FDG could be valuable in …

Fine-needle aspiration biopsy (FNAB) is inconclusive in up to 20% of patients with solitary
thyroid nodules. In these cases, hemithyroidectomy is necessary, but only 20% of the nodules …

A patient with long‐standing rheumatoid arthritis developed hypercalcemia (3.13 mmol/l)
and was subsequently found to have a B‐cell lymphoma (centroblastic type). The …

Background: Detection of incompletely processed precursor forms of insulin-like growth
factor-II (“big” IGF-II) in plasma is essential for both the diagnosis and follow-up of non-islet cell …

Thyroid disease can roughly be divided into functional and anatomical disorders. Subclinical
disease is by definition not accompanied by symptoms or signs and usually goes …

To the Editor: Gabapentin is a new anticonvulsive drug frequently used for the treatment of
various neuropathic pain conditions. 1–3 It is also increasingly used in palliative care. 4 …

Objective: To study the progression of hearing impairment (HI) and audiological features in
patients with the mitochondrial A to G mutation in the tRNA LEU (RUU) gene at position …

Acute pulmonary syndrome is an uncommon but severe adverse reaction to nitrofurantoin.
This syndrome is seldom recognised at the moment of presentation, which potentially …