User profiles for A. Bekier
Adrian BekierKlinika Immunologii i Alergii, Uniwersytet Medyczny w Łodzi Verified email at umed.lodz.pl Cited by 204 |
Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and …
A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of
novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and …
novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and …
[HTML][HTML] PPE51 Is Involved in the Uptake of Disaccharides by Mycobacterium tuberculosis
We have recently found that selected thio-disaccharides possess bactericidal effects against
Mycobacterium tuberculosis but not against Escherichia coli or Staphylococcus aureus. …
Mycobacterium tuberculosis but not against Escherichia coli or Staphylococcus aureus. …
[HTML][HTML] Benzo [b] thiophene-thiazoles as potent anti-Toxoplasma gondii agents: Design, synthesis, tyrosinase/tyrosine hydroxylase inhibitors, molecular docking …
B Rosada, A Bekier, J Cytarska, W Płaziński… - European Journal of …, 2019 - Elsevier
Synthesis and investigation of anti-Toxoplasma gondii activity of novel thiazoles containing
benzo [b]thiophene moiety are presented. Among the derivatives, compound 3k with …
benzo [b]thiophene moiety are presented. Among the derivatives, compound 3k with …
[HTML][HTML] Controlling the spatiotemporal release of nerve growth factor by chitosan/polycaprolactone conduits for use in peripheral nerve regeneration
…, M Wieczorek, S Michlewska, A Bekier… - International Journal of …, 2022 - mdpi.com
Tubular polymeric structures have been recognized in the treatment of peripheral nerves as
comparable to autologous grafting. The best therapeutic outcomes are obtained with …
comparable to autologous grafting. The best therapeutic outcomes are obtained with …
[HTML][HTML] Thiazoles with cyclopropyl fragment as antifungal, anticonvulsant, and anti-Toxoplasma gondii agents: synthesis, toxicity evaluation, and molecular docking …
Synthesis and investigation of antifungal, anticonvulsant and anti-Toxoplasma gondii activities
of ten novel (2-(cyclopropylmethylidene)hydrazinyl)thiazole 3a–3j are presented. Among …
of ten novel (2-(cyclopropylmethylidene)hydrazinyl)thiazole 3a–3j are presented. Among …
[HTML][HTML] Imidazole-Thiosemicarbazide Derivatives as Potent Anti-Mycobacterium tuberculosis Compounds with Antibiofilm Activity
Mycobacterium tuberculosis (Mtb) is an intracellular pathogenic bacterium and the causative
agent of tuberculosis. This disease is one of the most ancient and deadliest bacterial …
agent of tuberculosis. This disease is one of the most ancient and deadliest bacterial …
[HTML][HTML] 4-arylthiosemicarbazide derivatives as toxoplasmic aromatic amino acid hydroxylase inhibitors and anti-inflammatory agents
A Bekier, A Brzostek, A Paneth, B Dziadek… - International Journal of …, 2022 - mdpi.com
Approximately one-third of the human population is infected with the intracellular cosmopolitan
protozoan Toxoplasma gondii (Tg), and a specific treatment for this parasite is still needed…
protozoan Toxoplasma gondii (Tg), and a specific treatment for this parasite is still needed…
[HTML][HTML] Synthesis and In Vitro Anti-Toxoplasma gondii Activity of Novel Thiazolidin-4-one Derivatives
Recent findings on the biological activity of thiazolidin-4-ones and taking into account the
lack of effective drugs used in the treatment of toxoplasmosis, their numerous side effects, as …
lack of effective drugs used in the treatment of toxoplasmosis, their numerous side effects, as …
[HTML][HTML] Discovery of Potent and Selective Halogen-Substituted Imidazole-Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro via Structure-Based …
A Paneth, L Węglińska, A Bekier, E Stefaniszyn… - Molecules, 2019 - mdpi.com
Employing a simple synthetic protocol, a series of highly effective halogen-substituted
imidazole-thiosemicarbazides with anti-Toxoplasma gondii effects against the RH tachyzoites, …
imidazole-thiosemicarbazides with anti-Toxoplasma gondii effects against the RH tachyzoites, …
[HTML][HTML] Systematic Identification of Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro
A Paneth, L Węglińska, A Bekier, E Stefaniszyn… - Molecules, 2019 - mdpi.com
One of the key stages in the development of new therapies in the treatment of toxoplasmosis
is the identification of new non-toxic small molecules with high specificity to Toxoplasma …
is the identification of new non-toxic small molecules with high specificity to Toxoplasma …