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Imaging of human epidermal growth factor receptor type 2 expression with 18F-labeled affibody molecule ZHER2:2395 in a mouse model for ovarian cancer.

Heskamp S, Laverman P, Rosik D, Boschetti F, van der Graaf WT, Oyen WJ, van Laarhoven HW, Tolmachev V, Boerman OC. Heskamp S, et al. J Nucl Med. 2012 Jan;53(1):146-53. doi: 10.2967/jnumed.111.093047. Epub 2011 Dec 15. J Nucl Med. 2012. PMID: 22173842 Free article.

Three methods for 18F labeling of the HER2-binding affibody molecule Z(HER2:2891) including preclinical assessment.

Glaser M, Iveson P, Hoppmann S, Indrevoll B, Wilson A, Arukwe J, Danikas A, Bhalla R, Hiscock D. Glaser M, et al. J Nucl Med. 2013 Nov;54(11):1981-8. doi: 10.2967/jnumed.113.122465. Epub 2013 Oct 10. J Nucl Med. 2013. PMID: 24115530 Free article.

Synthesis, preclinical validation, dosimetry, and toxicity of 68Ga-NOTA-anti-HER2 Nanobodies for iPET imaging of HER2 receptor expression in cancer.

Xavier C, Vaneycken I, D'huyvetter M, Heemskerk J, Keyaerts M, Vincke C, Devoogdt N, Muyldermans S, Lahoutte T, Caveliers V. Xavier C, et al. J Nucl Med. 2013 May;54(5):776-84. doi: 10.2967/jnumed.112.111021. Epub 2013 Mar 13. J Nucl Med. 2013. PMID: 23487015 Free article.

HER2-positive tumors imaged within 1 hour using a site-specifically 11C-labeled Sel-tagged affibody molecule.

Wållberg H, Grafström J, Cheng Q, Lu L, Martinsson Ahlzén HS, Samén E, Thorell JO, Johansson K, Dunås F, Olofsson MH, Stone-Elander S, Arnér ES, Ståhl S. Wållberg H, et al. J Nucl Med. 2012 Sep;53(9):1446-53. doi: 10.2967/jnumed.111.102194. Epub 2012 Aug 7. J Nucl Med. 2012. PMID: 22872744 Free article.

Evaluation of the first ⁴⁴Sc-labeled Affibody molecule for imaging of HER2-expressing tumors.

Honarvar H, Müller C, Cohrs S, Haller S, Westerlund K, Karlström AE, van der Meulen NP, Schibli R, Tolmachev V. Honarvar H, et al. Nucl Med Biol. 2017 Feb;45:15-21. doi: 10.1016/j.nucmedbio.2016.10.004. Epub 2016 Oct 18. Nucl Med Biol. 2017. PMID: 27837664

PET of tumors expressing gastrin-releasing peptide receptor with an 18F-labeled bombesin analog.

Dijkgraaf I, Franssen GM, McBride WJ, D'Souza CA, Laverman P, Smith CJ, Goldenberg DM, Oyen WJ, Boerman OC. Dijkgraaf I, et al. J Nucl Med. 2012 Jun;53(6):947-52. doi: 10.2967/jnumed.111.100891. Epub 2012 May 8. J Nucl Med. 2012. PMID: 22570329 Free article.

Comparative in vivo evaluation of technetium and iodine labels on an anti-HER2 affibody for single-photon imaging of HER2 expression in tumors.

Orlova A, Nilsson FY, Wikman M, Widström C, Ståhl S, Carlsson J, Tolmachev V. Orlova A, et al. J Nucl Med. 2006 Mar;47(3):512-9. J Nucl Med. 2006. PMID: 16513621 Free article.

Targeting of HER2-expressing tumors with a site-specifically 99mTc-labeled recombinant affibody molecule, ZHER2:2395, with C-terminally engineered cysteine.

Ahlgren S, Wållberg H, Tran TA, Widström C, Hjertman M, Abrahmsén L, Berndorff D, Dinkelborg LM, Cyr JE, Feldwisch J, Orlova A, Tolmachev V. Ahlgren S, et al. J Nucl Med. 2009 May;50(5):781-9. doi: 10.2967/jnumed.108.056929. Epub 2009 Apr 16. J Nucl Med. 2009. PMID: 19372467 Free article.

Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting.

Hoppmann S, Miao Z, Liu S, Liu H, Ren G, Bao A, Cheng Z. Hoppmann S, et al. Bioconjug Chem. 2011 Mar 16;22(3):413-21. doi: 10.1021/bc100432h. Epub 2011 Feb 7. Bioconjug Chem. 2011. PMID: 21299201 Free PMC article.

Site-specific radiometal labeling and improved biodistribution using ABY-027, a novel HER2-targeting affibody molecule-albumin-binding domain fusion protein.

Orlova A, Jonsson A, Rosik D, Lundqvist H, Lindborg M, Abrahmsen L, Ekblad C, Frejd FY, Tolmachev V. Orlova A, et al. J Nucl Med. 2013 Jun;54(6):961-8. doi: 10.2967/jnumed.112.110700. Epub 2013 Mar 25. J Nucl Med. 2013. PMID: 23528382 Free article.

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