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16157541,17707805,23464855,12937948,16568203,10855644,16059963,23768172,15869461,9455802,20525456,18552141,23109400,15013489,12732671,15709181,10901448,23090293,19142704,10398816,12902423,9458086,10212119,16021448,9625504,12009943,16204724,12121126,25743164,21795364,22336375,12171531,10436200,8683294,11965608,11190491,18751394,10363797,19504168,9568060,12029547,15068614,18482677,12552352,12483418,9096086,10589778,17979564,17127166,20402463,17530247,15991301,24335877,9473268,16513620,11340564,9430472,11007513,21078795,15653653,19443580,12236784,10096494,11192715,22882936,9044843,26364504,30639635,17226960,19289435,17225119,16513623,26673241,17308920,25379612,16595488,20595511,8523125,11948475,15264875,10731786,27479886,15349959,27479884,11823119,17923824,10965902,12845487,10616889,15073269,15246375,20651367,10319747,17546456,16475719,15809493,25453052,7911760,11216519,24287321,17401086,16391196,9893158,17138746,16269604,20411957,16204720,18678351,15093822,12768332,16679728,19995807,22245688,7498221,15093821,31662215,17138750,21068709,22682002,12352601,27775943,17138748,20643121,12552343,10037188,17627424,30069789,19690033,15347722,9620621,15374988,16721571,23531772,11476164,36402025,21791941,16791800,25977461,36097232,23829459,31129499,31385111,26558391,17006849,12960199,35660705,11585290,11295426,16151771,1658516,10399029,29668724,12811420,30606385,21852357,18509636,10071756,17138743,21852355,15872355,15149184,16531924,23679852,17146655,20641776,22391705,18927338,15912401,31886756,15872353,15623652,17372571,12515881,15891599,22305264,11996325,18298335,17052612,14530481,20641749,14530465,19445476,15153445,28810154,16595502,22787691,11745491,32426902,27715017,14650159,28349291,15175836,30412382,14741567,32560611,24382404,11182566,11390562,30594453,12623112,10541822,15299065,19223405,11877760,20108938,10328231,28144828,24378707,30170196,15653647,21680701,29291444,24970911,29455647,25603866,20641296,21765239,30406512,12552341,21946438,16330570,17906380,8691466,31492994,22926735,20152715,9257325,16542847,26514177,11083550,17691760,22445386,9662587,18381940,21860334,26152564,23721625,9871736,1658515,17707803,23618768,26369025,17137786,18753829,30604401,17594090,27479887,25144854,28193503,18246556,23067692,10199941,18199616,12768330,17653543,20150268,21383640,12174893,17210459,10521803,25427548,16843838,36354685,11807604,17674000,20641350,24957558,12483404,28450554,7710334,18199624,18158950,8781146,15968595,15235063,17021817,21157213,15186597,28104744,23276828,12582815,16314738,22157022,28953210,12732683,15068619,14503955,19111046,22399589,14734660,29030760,31829777,16741314,26173620,11884499,23657621,35619201,7904561,27981843,10626285,9080482,17311765,15872348,11323230,27479790,18317293,27743210,24876207,16611856,18287262,30334858,33391488,23418722,28088445,19414394,28821003,25175799,12745013,30381892,8404961,15149193,20956465,15309330,15632044,24873792,16459268,33800582,24094076,16269603,18703613,16720240,21381408,17998094,18344429,28043006,15001692,17204710,18815662,11973491,28816013,12831983,16290170,28572490,32279449,26466867,27127222,11087333,15299064,20641372,19585115,25038907,17314591,15136637,11390557,33086272,7966134,21210566,26255282,20556233,21210567,16741313,28160666,16287258,15029461,19039561,17383581,19289419,17383578,23573294,16438887,18815676,11906276,16437406,11752087,29775901,16172569,21421708,32914391,22819251,12623113,27259576,19707908,25706799,15687327,17707799,26179963,15872364,21970835,25771369,25890861,11518648,15585485,25561916,22940856,25315509,29023951,36757034,9575243,36800496,10446977,28351606,36398935,22545083,17922063,20570022,12563141,27338334,30672760,17383579,17726664,26251418,26445336,29517903,17651043,22108870,32932783,20122665,20956468,33741866,8940709,16699765,29926342,12745016,29885559,21204758,23037700,11786281,24934713,21782912,16821789,14734679,17575235,24388591,18493690,20870154,15653666,8878464,15235069,9428601,8062850,29634355,11696645,30650563,16133391,16513612,23652209,22663248,17673999,16631091,25030395,9804043,20641431,22996234,11508787,21328514,25993108,16098291,7596072,30133308,26224936,26657220,10836705,14734682,31519803,12394124,16455643,35011496,32006673,20696224,7706986,25673264,27093344,29097943,27561428,24769333,16631092,11965610,11578896,8662116,18036826,15186602,11395318,11922209,27737549,21728843,28575794,30338432,33212346,8391831,12900286,10380832,16000291,25791453,32757150,16417269,30034278,21531292,11762351,27604575,20641328,19525474,15657509,7778214,21883013,12418470,9428603,17260467,22076978,17286235,27649935,18425512,21654355,16619112,8813461,27568083,16391200,10353735,8583329,18674722,33355247,16157539,24089059,27586132,32628464,18703609,19266197,29747035,27924732,12623116,34703406,29148726,21321259,11395313,27515713,34845659,20641374,12831982,11323245,35800424,12050331,12574972,9234331,26897009,28110557,12433051,16821593,15014904,15632045,8395748,22995625,21541533,30248495,18475055,25222910,19614681,22635083,22056254,12702954,26420336,29397911,17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Evaluation of [99mTc/EDDA/HYNIC0]octreotide derivatives compared with [111In-DOTA0,Tyr3, Thr8]octreotide and [111In-DTPA0]octreotide: does tumor or pancreas uptake correlate with the rate of internalization?

Storch D, Béhé M, Walter MA, Chen J, Powell P, Mikolajczak R, Mäcke HR. Storch D, et al. J Nucl Med. 2005 Sep;46(9):1561-9. J Nucl Med. 2005. PMID: 16157541 Free article.

Preclinical evaluation of [99mTc/EDDA/tricine/HYNIC0, 1-Nal3, Thr8]-octreotide as a new analogue in the detection of somatostatin-receptor-positive tumors.

Gandomkar M, Najafi R, Shafiei M, Mazidi M, Ebrahimi SE. Gandomkar M, et al. Nucl Med Biol. 2007 Aug;34(6):651-7. doi: 10.1016/j.nucmedbio.2007.06.006. Nucl Med Biol. 2007. PMID: 17707805

Preparation and biological evaluation of [(99m)Tc/EDDA/Tricine/HYNIC(0), BzThi(3)]-octreotide for somatostatin receptor-positive tumor imaging.

Erfani M, Shafiei M, Mazidi M, Goudarzi M. Erfani M, et al. Cancer Biother Radiopharm. 2013 Apr;28(3):240-7. doi: 10.1089/cbr.2012.1270. Epub 2013 Mar 6. Cancer Biother Radiopharm. 2013. PMID: 23464855

DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals.

Wild D, Schmitt JS, Ginj M, Mäcke HR, Bernard BF, Krenning E, De Jong M, Wenger S, Reubi JC. Wild D, et al. Eur J Nucl Med Mol Imaging. 2003 Oct;30(10):1338-47. doi: 10.1007/s00259-003-1255-5. Epub 2003 Aug 21. Eur J Nucl Med Mol Imaging. 2003. PMID: 12937948

[(99m)Tc]Demotate 2 in the detection of sst(2)-positive tumours: a preclinical comparison with [(111)In]DOTA-tate.

Maina T, Nock BA, Cordopatis P, Bernard BF, Breeman WA, van Gameren A, van den Berg R, Reubi JC, Krenning EP, de Jong M. Maina T, et al. Eur J Nucl Med Mol Imaging. 2006 Jul;33(7):831-40. doi: 10.1007/s00259-006-0068-8. Epub 2006 Mar 28. Eur J Nucl Med Mol Imaging. 2006. PMID: 16568203 Free article.

99mTc-HYNIC-[Tyr3]-octreotide for imaging somatostatin-receptor-positive tumors: preclinical evaluation and comparison with 111In-octreotide.

Decristoforo C, Melendez-Alafort L, Sosabowski JK, Mather SJ. Decristoforo C, et al. J Nucl Med. 2000 Jun;41(6):1114-9. J Nucl Med. 2000. PMID: 10855644 Free article.

Tetraamine-modified octreotide and octreotate: labeling with 99mTc and preclinical comparison in AR4-2J cells and AR4-2J tumor-bearing mice.

Nikolopoulou A, Maina T, Sotiriou P, Cordopatis P, Nock BA. Nikolopoulou A, et al. J Pept Sci. 2006 Feb;12(2):124-31. doi: 10.1002/psc.693. J Pept Sci. 2006. PMID: 16059963

(99m)Tc-labeled dimeric octreotide peptide: a radiotracer with high tumor uptake for single-photon emission computed tomography imaging of somatostatin receptor subtype 2-positive tumors.

Dong C, Zhao H, Yang S, Shi J, Huang J, Cui L, Zhong L, Jin X, Li F, Liu Z, Jia B, Wang F. Dong C, et al. Mol Pharm. 2013 Aug 5;10(8):2925-33. doi: 10.1021/mp400040z. Epub 2013 Jun 28. Mol Pharm. 2013. PMID: 23768172

Differences in biodistribution between 99mTc-depreotide, 111In-DTPA-octreotide, and 177Lu-DOTA-Tyr3-octreotate in a small cell lung cancer animal model.

Schmitt A, Bernhardt P, Nilsson O, Ahlman H, Kölby L, Forssell-Aronsson E. Schmitt A, et al. Cancer Biother Radiopharm. 2005 Apr;20(2):231-6. doi: 10.1089/cbr.2005.20.231. Cancer Biother Radiopharm. 2005. PMID: 15869461

Pre-clinical comparison of [DTPA0] octreotide, [DTPA0,Tyr3] octreotide and [DOTA0,Tyr3] octreotide as carriers for somatostatin receptor-targeted scintigraphy and radionuclide therapy.

De Jong M, Bakker WH, Breeman WA, Bernard BF, Hofland LJ, Visser TJ, Srinivasan A, Schmidt M, Béhé M, Mäcke HR, Krenning EP. De Jong M, et al. Int J Cancer. 1998 Jan 30;75(3):406-11. doi: 10.1002/(sici)1097-0215(19980130)75:3<406::aid-ijc14>3.0.co;2-6. Int J Cancer. 1998. PMID: 9455802 Free article.

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