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Page 1
New approaches in psychiatric drug development.
van der Doef TF, Zaragoza Domingo S, Jacobs GE, Drevets WC, Marston HM, Nathan PJ, Tome MB, Tamminga CA, van Gerven JMA, Kas MJH. van der Doef TF, et al. Eur Neuropsychopharmacol. 2018 Sep;28(9):983-993. doi: 10.1016/j.euroneuro.2018.06.006. Epub 2018 Jul 25. Eur Neuropsychopharmacol. 2018. PMID: 30056086 Review.
Microglial activation in healthy aging.
Schuitemaker A, van der Doef TF, Boellaard R, van der Flier WM, Yaqub M, Windhorst AD, Barkhof F, Jonker C, Kloet RW, Lammertsma AA, Scheltens P, van Berckel BN. Schuitemaker A, et al. Among authors: van der doef tf. Neurobiol Aging. 2012 Jun;33(6):1067-72. doi: 10.1016/j.neurobiolaging.2010.09.016. Epub 2010 Nov 3. Neurobiol Aging. 2012. PMID: 21051106
Quantification of the novel N-methyl-d-aspartate receptor ligand [11C]GMOM in man.
van der Doef TF, Golla SSV, Klein PJ, Oropeza-Seguias GM, Schuit RC, Metaxas A, Jobse E, Schwarte LA, Windhorst AD, Lammertsma AA, van Berckel BNM, Boellaard R. van der Doef TF, et al. J Cereb Blood Flow Metab. 2016 Jun;36(6):1111-21. doi: 10.1177/0271678X15608391. Epub 2015 Oct 5. J Cereb Blood Flow Metab. 2016. PMID: 26661185 Free PMC article.
Human Dosimetry of the N-Methyl-d-Aspartate Receptor Ligand 11C-GMOM.
van der Aart J, van der Doef TF, Horstman P, Huisman MC, Schuit RC, van Lingen A, Windhorst AD, van Berckel BNM, Lammertsma AA. van der Aart J, et al. Among authors: van der doef tf. J Nucl Med. 2017 Aug;58(8):1330-1333. doi: 10.2967/jnumed.116.188250. Epub 2017 Feb 9. J Nucl Med. 2017. PMID: 28183990 Free article. Clinical Trial.
Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder.
Denys D, de Vries F, Cath D, Figee M, Vulink N, Veltman DJ, van der Doef TF, Boellaard R, Westenberg H, van Balkom A, Lammertsma AA, van Berckel BN. Denys D, et al. Among authors: van der doef tf. Eur Neuropsychopharmacol. 2013 Nov;23(11):1423-31. doi: 10.1016/j.euroneuro.2013.05.012. Epub 2013 Jul 19. Eur Neuropsychopharmacol. 2013. PMID: 23876376 Free article.
First-in-man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M1 -receptor partial agonist for the treatment of dementias.
Bakker C, Tasker T, Liptrot J, Hart EP, Klaassen ES, Prins S, van der Doef TF, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Cross DM, Groeneveld GJ, Nathan PJ. Bakker C, et al. Among authors: van der doef tf. Br J Clin Pharmacol. 2021 Jul;87(7):2945-2955. doi: 10.1111/bcp.14710. Epub 2021 Feb 5. Br J Clin Pharmacol. 2021. PMID: 33351971 Free PMC article. Clinical Trial.
Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study.
Schuitemaker A, Kropholler MA, Boellaard R, van der Flier WM, Kloet RW, van der Doef TF, Knol DL, Windhorst AD, Luurtsema G, Barkhof F, Jonker C, Lammertsma AA, Scheltens P, van Berckel BN. Schuitemaker A, et al. Among authors: van der doef tf. Neurobiol Aging. 2013 Jan;34(1):128-36. doi: 10.1016/j.neurobiolaging.2012.04.021. Epub 2012 Jul 26. Neurobiol Aging. 2013. PMID: 22840559 Free article.