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Page 1
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, Fumagalli L, Hersmus N, Janky R, Impens F, Vanden Berghe P, Ho R, Thal DR, Vandenberghe R, Hegde ML, Chandran S, De Strooper B, Daelemans D, Van Damme P, Van Den Bosch L, Verfaillie C. Guo W, et al. Among authors: van schoor e. Alzheimers Dement. 2023 Apr;19(4):1245-1259. doi: 10.1002/alz.12760. Epub 2022 Aug 22. Alzheimers Dement. 2023. PMID: 35993441 Free PMC article.
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.
Koper MJ, Tomé SO, Gawor K, Belet A, Van Schoor E, Schaeverbeke J, Vandenberghe R, Vandenbulcke M, Ghebremedhin E, Otto M, von Arnim CAF, Balusu S, Blaschko MB, De Strooper B, Thal DR. Koper MJ, et al. Among authors: van schoor e. Acta Neuropathol Commun. 2022 Sep 3;10(1):128. doi: 10.1186/s40478-022-01432-6. Acta Neuropathol Commun. 2022. PMID: 36057624 Free PMC article.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Braems E, Bercier V, Van Schoor E, Heeren K, Beckers J, Fumagalli L, Dedeene L, Moisse M, Geudens I, Hersmus N, Mehta AR, Selvaraj BT, Chandran S, Ho R, Thal DR, Van Damme P, Swinnen B, Van Den Bosch L. Braems E, et al. Among authors: van schoor e. Acta Neuropathol. 2022 Sep;144(3):465-488. doi: 10.1007/s00401-022-02471-y. Epub 2022 Jul 27. Acta Neuropathol. 2022. PMID: 35895140 Free PMC article.
TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study.
Van Weehaeghe D, Van Schoor E, De Vocht J, Koole M, Attili B, Celen S, Declercq L, Thal DR, Van Damme P, Bormans G, Van Laere K. Van Weehaeghe D, et al. Among authors: van schoor e. J Nucl Med. 2020 Apr;61(4):604-607. doi: 10.2967/jnumed.119.231985. Epub 2019 Sep 27. J Nucl Med. 2020. PMID: 31562223 Free PMC article.
16 results