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Systemic overexpression of interleukin-22 induces the negative immune-regulator SOCS3 and potently reduces experimental arthritis in mice.
Aarts J, Roeleveld DM, Helsen MM, Walgreen B, Vitters EL, Kolls J, van de Loo FA, van Lent PL, van der Kraan PM, Koenders MI. Aarts J, et al. Among authors: roeleveld dm. Rheumatology (Oxford). 2021 Apr 6;60(4):1974-1983. doi: 10.1093/rheumatology/keaa589. Rheumatology (Oxford). 2021. PMID: 33197269 Free PMC article.
Imaging fibroblast activation protein to monitor therapeutic effects of neutralizing interleukin-22 in collagen-induced arthritis.
van der Geest T, Roeleveld DM, Walgreen B, Helsen MM, Nayak TK, Klein C, Hegen M, Storm G, Metselaar JM, van den Berg WB, van der Kraan PM, Laverman P, Boerman OC, Koenders MI. van der Geest T, et al. Among authors: roeleveld dm. Rheumatology (Oxford). 2018 Apr 1;57(4):737-747. doi: 10.1093/rheumatology/kex456. Rheumatology (Oxford). 2018. PMID: 29361119
In Vivo Imaging of Antileukemic Drug Asparaginase Reveals a Rapid Macrophage-Mediated Clearance from the Bone Marrow.
van der Meer LT, Terry SY, van Ingen Schenau DS, Andree KC, Franssen GM, Roeleveld DM, Metselaar JM, Reinheckel T, Hoogerbrugge PM, Boerman OC, van Leeuwen FN. van der Meer LT, et al. Among authors: roeleveld dm. J Nucl Med. 2017 Feb;58(2):214-220. doi: 10.2967/jnumed.116.177741. Epub 2016 Aug 4. J Nucl Med. 2017. PMID: 27493268 Free article.
Interleukin-21 receptor deficiency increases the initial toll-like receptor 2 response but protects against joint pathology by reducing Th1 and Th17 cells during streptococcal cell wall arthritis.
Marijnissen RJ, Roeleveld DM, Young D, Nickerson-Nutter C, Abdollahi-Roodsaz S, Garcia de Aquino S, van de Loo FA, van Spriel AB, Boots AM, van den Berg WB, Koenders MI. Marijnissen RJ, et al. Among authors: roeleveld dm. Arthritis Rheumatol. 2014 Apr;66(4):886-95. doi: 10.1002/art.38312. Arthritis Rheumatol. 2014. PMID: 24757141