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Conformationally constrained analogues of bleomycin A5.
Rishel MJ, Thomas CJ, Tao ZF, Vialas C, Leitheiser CJ, Hecht SM. Rishel MJ, et al. J Am Chem Soc. 2003 Aug 27;125(34):10194-205. doi: 10.1021/ja030057w. J Am Chem Soc. 2003. PMID: 12926941
The disaccharide moiety of bleomycin facilitates uptake by cancer cells.
Schroeder BR, Ghare MI, Bhattacharya C, Paul R, Yu Z, Zaleski PA, Bozeman TC, Rishel MJ, Hecht SM. Schroeder BR, et al. Among authors: rishel mj. J Am Chem Soc. 2014 Oct 1;136(39):13641-56. doi: 10.1021/ja507255g. Epub 2014 Sep 23. J Am Chem Soc. 2014. PMID: 25184545 Free PMC article.
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