Pryyma A[au] - Search Results

Year	Number of Results
2015	1
2018	1
2019	2
2020	2
2021	3
2022	2
2024	1

1

Rationally Designed Amanitins Achieve Enhanced Cytotoxicity.

Todorovic M, Rivollier P, Wong AAWL, Wang Z, Pryyma A, Nguyen TT, Newell KC, Froelich J, Perrin DM. Todorovic M, et al. Among authors: pryyma a. J Med Chem. 2022 Aug 11;65(15):10357-10376. doi: 10.1021/acs.jmedchem.1c02226. Epub 2022 Jun 13. J Med Chem. 2022. PMID: 35696491

2

Synthesis of the Death-Cap Mushroom Toxin α-Amanitin.

Matinkhoo K, Pryyma A, Todorovic M, Patrick BO, Perrin DM. Matinkhoo K, et al. Among authors: pryyma a. J Am Chem Soc. 2018 May 30;140(21):6513-6517. doi: 10.1021/jacs.7b12698. Epub 2018 Mar 21. J Am Chem Soc. 2018. PMID: 29561592

3

Rapid, High-Yielding Solid-Phase Synthesis of Cathepsin-B Cleavable Linkers for Targeted Cancer Therapeutics.

Pryyma A, Gunasekera S, Lewin J, Perrin DM. Pryyma A, et al. Bioconjug Chem. 2020 Dec 16;31(12):2685-2690. doi: 10.1021/acs.bioconjchem.0c00563. Epub 2020 Dec 4. Bioconjug Chem. 2020. PMID: 33274932

4

Synthesis of a Cytotoxic Amanitin for Biorthogonal Conjugation.

Zhao L, May JP, Blanc A, Dietrich DJ, Loonchanta A, Matinkhoo K, Pryyma A, Perrin DM. Zhao L, et al. Among authors: pryyma a. Chembiochem. 2015 Jul 6;16(10):1420-5. doi: 10.1002/cbic.201500226. Epub 2015 Jun 3. Chembiochem. 2015. PMID: 26043184

5

Synthesis and preliminary evaluation of octreotate conjugates of bioactive synthetic amatoxins for targeting somatostatin receptor (sstr2) expressing cells.

Pryyma A, Matinkhoo K, Bu YJ, Merkens H, Zhang Z, Bénard F, Perrin DM. Pryyma A, et al. RSC Chem Biol. 2021 Oct 7;3(1):69-78. doi: 10.1039/d1cb00036e. eCollection 2022 Jan 5. RSC Chem Biol. 2021. PMID: 35128410 Free PMC article.

6

Synthesis and evaluation of "Ama-Flash", a photocaged amatoxin prodrug for light-activated RNA Pol II inhibition and cell death.

Matinkhoo K, Pryyma A, Wong AAWL, Perrin DM. Matinkhoo K, et al. Among authors: pryyma a. Chem Commun (Camb). 2021 Sep 21;57(75):9558-9561. doi: 10.1039/d1cc03279h. Chem Commun (Camb). 2021. PMID: 34477193

7

One-Step ¹⁸F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging.

Kuo HT, Lepage ML, Lin KS, Pan J, Zhang Z, Liu Z, Pryyma A, Zhang C, Merkens H, Roxin A, Perrin DM, Bénard F. Kuo HT, et al. Among authors: pryyma a. J Nucl Med. 2019 Aug;60(8):1160-1166. doi: 10.2967/jnumed.118.216598. Epub 2019 Feb 8. J Nucl Med. 2019. PMID: 30737299 Free PMC article.

8

Diphenylphosphinylhydroxylamine (DPPH) Affords Late-Stage S-imination to access free-NH Sulfilimines and Sulfoximines.

Gunasekera S, Pryyma A, Jung J, Greenwood R, Patrick BO, Perrin DM. Gunasekera S, et al. Among authors: pryyma a. Angew Chem Int Ed Engl. 2024 Mar 22;63(13):e202314906. doi: 10.1002/anie.202314906. Epub 2024 Feb 19. Angew Chem Int Ed Engl. 2024. PMID: 38289976

9

Scaling Amatoxin Synthesis with an Improved Route to (2S,3R,4R)-Dihydroxyisoleucine Exemplified by a Toxic, Clickable α-Amanitin Analogue.

Hambira CM, Matinkhoo K, Pryyma A, Patrick BO, Perrin DM. Hambira CM, et al. Among authors: pryyma a. J Org Chem. 2021 Apr 2;86(7):5362-5370. doi: 10.1021/acs.joc.0c03022. Epub 2021 Mar 12. J Org Chem. 2021. PMID: 33710901

10

Meeting key synthetic challenges in amanitin synthesis with a new cytotoxic analog: 5'-hydroxy-6'-deoxy-amanitin.

Pryyma A, Matinkhoo K, Wong AAWL, Perrin DM. Pryyma A, et al. Chem Sci. 2020 Oct 15;11(43):11927-11935. doi: 10.1039/d0sc04150e. Chem Sci. 2020. PMID: 34094418 Free PMC article.

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