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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2002 1
2004 2
2009 2
2011 1
2012 5
2013 1
2015 1
2016 4
2017 5
2018 7
2019 3
2020 3
2021 1
2024 0

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34 results

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Page 1
Increased building block access through collaboration.
Helal CJ, Bartolozzi A, Goble SD, Mani NS, Guzman-Perez A, Ohri AK, Shi ZC, Subramanyam C. Helal CJ, et al. Drug Discov Today. 2018 Aug;23(8):1458-1462. doi: 10.1016/j.drudis.2018.03.001. Epub 2018 Mar 20. Drug Discov Today. 2018. PMID: 29571837 Review. No abstract available.
Synthetic Approaches to the New Drugs Approved During 2017.
Flick AC, Leverett CA, Ding HX, McInturff E, Fink SJ, Helal CJ, O'Donnell CJ. Flick AC, et al. Among authors: helal cj. J Med Chem. 2019 Aug 22;62(16):7340-7382. doi: 10.1021/acs.jmedchem.9b00196. Epub 2019 Apr 15. J Med Chem. 2019. PMID: 30939001 Review.
Synthetic Approaches to New Drugs Approved during 2018.
Flick AC, Leverett CA, Ding HX, McInturff E, Fink SJ, Helal CJ, DeForest JC, Morse PD, Mahapatra S, O'Donnell CJ. Flick AC, et al. Among authors: helal cj. J Med Chem. 2020 Oct 8;63(19):10652-10704. doi: 10.1021/acs.jmedchem.0c00345. Epub 2020 May 22. J Med Chem. 2020. PMID: 32338902
5-Aryltetrazoles from Direct C-H Arylation with Aryl Bromides.
Zhang Y, Lee JCH, Reese MR, Boscoe BP, Humphrey JM, Helal CJ. Zhang Y, et al. Among authors: helal cj. J Org Chem. 2020 Apr 17;85(8):5718-5723. doi: 10.1021/acs.joc.0c00085. Epub 2020 Mar 31. J Org Chem. 2020. PMID: 32208719
Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality.
Butler CR, Ogilvie K, Martinez-Alsina L, Barreiro G, Beck EM, Nolan CE, Atchison K, Benvenuti E, Buzon L, Doran S, Gonzales C, Helal CJ, Hou X, Hsu MH, Johnson EF, Lapham K, Lanyon L, Parris K, O'Neill BT, Riddell D, Robshaw A, Vajdos F, Brodney MA. Butler CR, et al. Among authors: helal cj. J Med Chem. 2017 Jan 12;60(1):386-402. doi: 10.1021/acs.jmedchem.6b01451. Epub 2016 Dec 20. J Med Chem. 2017. PMID: 27997172 Free PMC article.
High-Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates.
Clement HA, Boghi M, McDonald RM, Bernier L, Coe JW, Farrell W, Helal CJ, Reese MR, Sach NW, Lee JC, Hall DG. Clement HA, et al. Among authors: helal cj. Angew Chem Int Ed Engl. 2019 Dec 16;58(51):18405-18409. doi: 10.1002/anie.201909308. Epub 2019 Oct 31. Angew Chem Int Ed Engl. 2019. PMID: 31591755
Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy.
Pettersson M, Johnson DS, Rankic DA, Kauffman GW, Am Ende CW, Butler TW, Boscoe B, Evrard E, Helal CJ, Humphrey JM, Stepan AF, Stiff CM, Yang E, Xie L, Bales KR, Hajos-Korcsok E, Jenkinson S, Pettersen B, Pustilnik LR, Ramirez DS, Steyn SJ, Wood KM, Verhoest PR. Pettersson M, et al. Among authors: helal cj. Medchemcomm. 2016 Nov 2;8(4):730-743. doi: 10.1039/c6md00406g. eCollection 2017 Apr 1. Medchemcomm. 2016. PMID: 30108792 Free PMC article.
Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE.
Seneviratne U, Huang Z, Am Ende CW, Butler TW, Cleary L, Dresselhaus E, Evrard E, Fisher EL, Green ME, Helal CJ, Humphrey JM, Lanyon LF, Marconi M, Mukherjee P, Sciabola S, Steppan CM, Sylvain EK, Tuttle JB, Verhoest PR, Wager TT, Xie L, Ramaswamy G, Johnson DS, Pettersson M. Seneviratne U, et al. Among authors: helal cj. Cell Chem Biol. 2021 Feb 18;28(2):148-157.e7. doi: 10.1016/j.chembiol.2020.09.002. Epub 2020 Sep 29. Cell Chem Biol. 2021. PMID: 32997975 Free article.
34 results