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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1982 2
1984 3
1985 3
1986 2
1987 1
1988 1
1989 1
1990 3
1991 1
1992 3
1993 5
1994 3
1995 3
1996 2
1997 3
1998 2
1999 1
2000 2
2001 2
2003 1
2004 6
2005 1
2007 1
2008 3
2009 2
2010 5
2011 9
2012 10
2013 7
2015 4
2016 8
2017 5
2018 3
2019 3
2020 2
2021 3
2022 3
2023 3
2024 2

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110 results

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Page 1
Neutrophil elastase inhibitors.
Groutas WC, Dou D, Alliston KR. Groutas WC, et al. Expert Opin Ther Pat. 2011 Mar;21(3):339-54. doi: 10.1517/13543776.2011.551115. Epub 2011 Jan 16. Expert Opin Ther Pat. 2011. PMID: 21235378 Free PMC article. Review.
Anti-norovirus therapeutics: a patent review (2010-2015).
Galasiti Kankanamalage AC, Weerawarna PM, Kim Y, Chang KO, Groutas WC. Galasiti Kankanamalage AC, et al. Among authors: groutas wc. Expert Opin Ther Pat. 2016;26(3):297-308. doi: 10.1517/13543776.2016.1153065. Expert Opin Ther Pat. 2016. PMID: 26881878 Free PMC article. Review.
Recent Advances in the Discovery of Norovirus Therapeutics.
Kim Y, Galasiti Kankanamalage AC, Chang KO, Groutas WC. Kim Y, et al. Among authors: groutas wc. J Med Chem. 2015 Dec 24;58(24):9438-50. doi: 10.1021/acs.jmedchem.5b00762. Epub 2015 Aug 17. J Med Chem. 2015. PMID: 26258852 Free PMC article. Review.
Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV).
Dampalla CS, Miller MJ, Kim Y, Zabiegala A, Nguyen HN, Madden TK, Thurman HA, Machen AJ, Cooper A, Liu L, Battaile KP, Lovell S, Chang KO, Groutas WC. Dampalla CS, et al. Among authors: groutas wc. Eur J Med Chem. 2023 Jun 5;254:115376. doi: 10.1016/j.ejmech.2023.115376. Epub 2023 Apr 15. Eur J Med Chem. 2023. PMID: 37080108 Free PMC article.
Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.
Rathnayake AD, Kim Y, Dampalla CS, Nguyen HN, Jesri AM, Kashipathy MM, Lushington GH, Battaile KP, Lovell S, Chang KO, Groutas WC. Rathnayake AD, et al. Among authors: groutas wc. J Med Chem. 2020 Oct 22;63(20):11945-11963. doi: 10.1021/acs.jmedchem.0c01252. Epub 2020 Oct 2. J Med Chem. 2020. PMID: 32945669
Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease.
Dampalla CS, Rathnayake AD, Galasiti Kankanamalage AC, Kim Y, Perera KD, Nguyen HN, Miller MJ, Madden TK, Picard HR, Thurman HA, Kashipathy MM, Liu L, Battaile KP, Lovell S, Chang KO, Groutas WC. Dampalla CS, et al. Among authors: groutas wc. J Med Chem. 2022 Jun 9;65(11):7818-7832. doi: 10.1021/acs.jmedchem.2c00224. Epub 2022 May 31. J Med Chem. 2022. PMID: 35638577 Free PMC article.
Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies.
Dampalla CS, Nguyen HN, Rathnayake AD, Kim Y, Perera KD, Madden TK, Thurman HA, Machen AJ, Kashipathy MM, Liu L, Battaile KP, Lovell S, Chang KO, Groutas WC. Dampalla CS, et al. Among authors: groutas wc. ACS Pharmacol Transl Sci. 2022 Dec 28;6(1):181-194. doi: 10.1021/acsptsci.2c00206. eCollection 2023 Jan 13. ACS Pharmacol Transl Sci. 2022. PMID: 36654747 Free PMC article.
Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.
Dampalla CS, Rathnayake AD, Perera KD, Jesri AM, Nguyen HN, Miller MJ, Thurman HA, Zheng J, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Kim Y, Groutas WC, Chang KO. Dampalla CS, et al. Among authors: groutas wc. J Med Chem. 2021 Dec 23;64(24):17846-17865. doi: 10.1021/acs.jmedchem.1c01037. Epub 2021 Dec 5. J Med Chem. 2021. PMID: 34865476 Free PMC article.
110 results