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Classes of Drugs that Mitigate Radiation Syndromes.
Micewicz ED, Damoiseaux RD, Deng G, Gomez A, Iwamoto KS, Jung ME, Nguyen C, Norris AJ, Ratikan JA, Ruchala P, Sayre JW, Schaue D, Whitelegge JP, McBride WH. Micewicz ED, et al. Among authors: damoiseaux rd. Front Pharmacol. 2021 May 18;12:666776. doi: 10.3389/fphar.2021.666776. eCollection 2021. Front Pharmacol. 2021. PMID: 34084139 Free PMC article.
4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.
Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. Micewicz ED, et al. Among authors: damoiseaux rd. PLoS One. 2017 Jul 21;12(7):e0181577. doi: 10.1371/journal.pone.0181577. eCollection 2017. PLoS One. 2017. PMID: 28732024 Free PMC article.
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.
Garcia G Jr, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. Garcia G Jr, et al. Among authors: damoiseaux rd. Cell Rep. 2021 Apr 6;35(1):108940. doi: 10.1016/j.celrep.2021.108940. Epub 2021 Mar 18. Cell Rep. 2021. PMID: 33784499 Free PMC article.
The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation.
Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. Micewicz ED, et al. Among authors: damoiseaux rd. Radiat Res. 2019 Apr;191(4):323-334. doi: 10.1667/RR15231.1. Epub 2019 Feb 7. Radiat Res. 2019. PMID: 30730284 Free PMC article.
Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma.
Kalbasi A, Tariveranmoshabad M, Hakimi K, Kremer S, Campbell KM, Funes JM, Vega-Crespo A, Parisi G, Champekar A, Nguyen C, Torrejon D, Shin D, Zaretsky JM, Damoiseaux RD, Speiser DE, Lopez-Casas PP, Quintero M, Ribas A. Kalbasi A, et al. Among authors: damoiseaux rd. Sci Transl Med. 2020 Oct 14;12(565):eabb0152. doi: 10.1126/scitranslmed.abb0152. Sci Transl Med. 2020. PMID: 33055240 Free PMC article.
Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner.
Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr. Koziol-White CJ, et al. Among authors: damoiseaux rd. Br J Pharmacol. 2016 Sep;173(18):2726-38. doi: 10.1111/bph.13542. Epub 2016 Aug 3. Br J Pharmacol. 2016. PMID: 27352269 Free PMC article.
Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.
Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA 3rd, Yokosuka O, Pandol SJ, Gukovskaya AS. Ohno I, et al. Among authors: damoiseaux rd. Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G63-73. doi: 10.1152/ajpgi.00257.2009. Epub 2009 Sep 17. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 19762431 Free PMC article.
Metabolic imaging allows early prediction of response to vandetanib.
Walter MA, Benz MR, Hildebrandt IJ, Laing RE, Hartung V, Damoiseaux RD, Bockisch A, Phelps ME, Czernin J, Weber WA. Walter MA, et al. Among authors: damoiseaux rd. J Nucl Med. 2011 Feb;52(2):231-40. doi: 10.2967/jnumed.110.081745. Epub 2011 Jan 13. J Nucl Med. 2011. PMID: 21233183 Free article.