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In search of preclinical robustness.
Peers IS, Ceuppens PR, Harbron C. Peers IS, et al. Among authors: ceuppens pr. Nat Rev Drug Discov. 2012 Oct;11(10):733-4. doi: 10.1038/nrd3849. Nat Rev Drug Discov. 2012. PMID: 23023666
Can you trust your animal study data?
Peers IS, South MC, Ceuppens PR, Bright JD, Pilling E. Peers IS, et al. Among authors: ceuppens pr. Nat Rev Drug Discov. 2014 Jul;13(7):560. doi: 10.1038/nrd4090-c1. Epub 2014 Jun 6. Nat Rev Drug Discov. 2014. PMID: 24903777 No abstract available.
Continuous inhibition of 11β-hydroxysteroid dehydrogenase type I in adipose tissue leads to tachyphylaxis in humans and rats but not in mice.
Morentin Gutierrez P, Gyte A, deSchoolmeester J, Ceuppens P, Swales J, Stacey C, Eriksson JW, Sjöstrand M, Nilsson C, Leighton B. Morentin Gutierrez P, et al. Among authors: ceuppens p. Br J Pharmacol. 2015 Oct;172(20):4806-16. doi: 10.1111/bph.13251. Epub 2015 Oct 8. Br J Pharmacol. 2015. PMID: 26218540 Free PMC article. Clinical Trial.
13 results