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Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs.
Seo JW, Ajenjo J, Wu B, Robinson E, Raie MN, Wang J, Tumbale SK, Buccino P, Anders DA, Shen B, Habte FG, Beinat C, James ML, Reyes ST, Ravindra Kumar S, Miles TF, Lee JT, Gradinaru V, Ferrara KW. Seo JW, et al. Among authors: buccino p. Biomaterials. 2022 Sep;288:121701. doi: 10.1016/j.biomaterials.2022.121701. Epub 2022 Aug 6. Biomaterials. 2022. PMID: 35985893 Free PMC article.
Radiosynthesis and initial preclinical evaluation of [11C]AZD1283 as a potential P2Y12R PET radiotracer.
Jackson IM, Buccino PJ, Azevedo EC, Carlson ML, Luo ASZ, Deal EM, Kalita M, Reyes ST, Shao X, Beinat C, Nagy SC, Chaney AM, Anders DA, Scott PJH, Smith M, Shen B, James ML. Jackson IM, et al. Among authors: buccino pj. Nucl Med Biol. 2022 Nov-Dec;114-115:143-150. doi: 10.1016/j.nucmedbio.2022.05.001. Epub 2022 May 20. Nucl Med Biol. 2022. PMID: 35680502 Free PMC article.
A Clinical PET Imaging Tracer ([18F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma.
Beinat C, Patel CB, Haywood T, Murty S, Naya L, Castillo JB, Reyes ST, Phillips M, Buccino P, Shen B, Park JH, Koran MEI, Alam IS, James ML, Holley D, Halbert K, Gandhi H, He JQ, Granucci M, Johnson E, Liu DD, Uchida N, Sinha R, Chu P, Born DE, Warnock GI, Weissman I, Hayden-Gephart M, Khalighi M, Massoud TF, Iagaru A, Davidzon G, Thomas R, Nagpal S, Recht LD, Gambhir SS. Beinat C, et al. Among authors: buccino p. Clin Cancer Res. 2021 Dec 1;27(23):6467-6478. doi: 10.1158/1078-0432.CCR-21-0544. Epub 2021 Sep 2. Clin Cancer Res. 2021. PMID: 34475101 Free PMC article.
Synthesis and biological properties of new 5-nitroindazole derivatives.
Arán VJ, Ochoa C, Boiani L, Buccino P, Cerecetto H, Gerpe A, González M, Montero D, Nogal JJ, Gómez-Barrio A, Azqueta A, López de Ceráin A, Piro OE, Castellano EE. Arán VJ, et al. Among authors: buccino p. Bioorg Med Chem. 2005 May 2;13(9):3197-207. doi: 10.1016/j.bmc.2005.02.043. Bioorg Med Chem. 2005. PMID: 15809155