Monte Carlo-assisted voxel source kernel method (MAVSK) for internal beta dosimetry

Nucl Med Biol. 1998 May;25(4):423-33. doi: 10.1016/s0969-8051(98)00002-x.

Abstract

A method is described for the determination of patient-specific organ beta doses given a known cumulated internal radioactivity distribution. A voxel source kernel for 90Y analogous to the point source function was simulated. Dose to each organ of interest could then be estimated by convolving the voxel source kernel with the patient's 3-D volume with known radioactivity assigned to each voxel. The dose calculation on eight organs took less than 1 min per patient using a Sun Sparc10 workstation.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Humans
  • Monte Carlo Method*
  • Neoplasms / radiotherapy*
  • Radioimmunotherapy / methods*
  • Radiotherapy Planning, Computer-Assisted*
  • Yttrium Radioisotopes

Substances

  • Yttrium Radioisotopes