Lack of association between dopamine transporter gene polymorphisms and delusional disorder

A M Persico; M Catalano

Lack of association between dopamine transporter gene polymorphisms and delusional disorder

Am J Med Genet. 1998 Mar 28;81(2):163-5.

Authors

A M Persico¹, M Catalano

Affiliation

¹ Department of NeuroPsychiatric Sciences, S. Raffaele Hospital, Milan, Italy. liucbm@iasi.rm.cnr.it

PMID: 9613856

Abstract

Potential contributions of dopamine transporter (DAT) gene variants to delusional disorder were investigated using association analysis. DAT gene VNTR polymorphisms were assessed in 61 delusional patients and 54 normal controls. No differences were found in either genotypic or allelic distributions. These findings do not support relevant contributions of DAT gene variants to the pathogenesis of delusional disorder.

MeSH terms

Adult
Aged
Alleles
Carrier Proteins / genetics*
Case-Control Studies
Dopamine Plasma Membrane Transport Proteins
Female
Genotype
Humans
Male
Membrane Glycoproteins*
Membrane Transport Proteins*
Middle Aged
Minisatellite Repeats*
Nerve Tissue Proteins*
Polymorphism, Genetic*
Schizophrenia, Paranoid / genetics*

Substances

Carrier Proteins
Dopamine Plasma Membrane Transport Proteins
Membrane Glycoproteins
Membrane Transport Proteins
Nerve Tissue Proteins
SLC6A3 protein, human