Strength in numbers: non-natural polyvalent carbohydrate derivatives

Chem Biol. 1996 Feb;3(2):71-7. doi: 10.1016/s1074-5521(96)90280-x.

Abstract

Many processes mediated by protein-carbohydrate interactions involve multivalent low-affinity binding, which is inherently difficult to study. New structural templates for the generation of multivalent carbohydrate displays have recently been developed, and tailored multivalent saccharide derivatives can now be used to study and modulate a wide variety of biological recognition events.

MeSH terms

  • Carbohydrate Metabolism
  • Carbohydrates / chemistry*
  • Protein Binding
  • Proteins / metabolism

Substances

  • Carbohydrates
  • Proteins