Acquisition and measurement of left ventricular (LV) volumes with a three-dimensional data set of cine magnetic resonance (MR) images from apex to base is a time-consuming process. Results of a study with 10 healthy volunteers and 10 patients with LV hypertrophy were prospectively evaluated. The heart was shown in the anatomic short- and horizontal long-axis planes with cine MR imaging. LV volumes were measured with various geometric models, and ejection fractions were calculated. In both groups, the values of LV stroke volume obtained with a modified Simpson rule and biplane ellipsoid models correlated well to the analysis of the three-dimensional data set of cine MR images. There were no significant differences for the calculated ejection fraction between values obtained with the modified Simpson rule or the biplane ellipsoid model versus the three-dimensional data set. A high inter-observer reproducibility of cine MR measurements with the two former models was found. Therefore, modified Simpson rule and biplane ellipsoid models, with their shorter acquisition and processing times, may increase the clinical utility of cine MR imaging.