Two female patients with breast cancer and axillary lymph node metastases had Tc-99m MIBI chest scintigraphy. The Tc-99m MIBI uptake in the primary breast cancer and metastatic lymph nodes were noted and discussed. The findings suggest that Tc-99m MIBI chest scintigraphy for palpable breast masses and axillary lymph nodes is a helpful test in detecting malignant breast masses and metastatic lymph nodes.