Metabolism and distribution of labeled theophylline in the pregnant rat. Impairment of theophylline metabolism by pregnancy and absence of a blood-brain barrier in the fetus

Pediatr Res. 1982 Mar;16(3):167-71. doi: 10.1203/00006450-198203000-00001.
No abstract available

MeSH terms

  • Animals
  • Blood-Brain Barrier
  • Brain Chemistry
  • Caffeine / metabolism
  • Female
  • Fetus / drug effects*
  • Maternal-Fetal Exchange
  • Pregnancy
  • Pregnancy, Animal*
  • Rats
  • Rats, Inbred Strains
  • Theophylline / blood
  • Theophylline / metabolism*
  • Theophylline / urine
  • Tissue Distribution

Substances

  • Caffeine
  • Theophylline