Abstract
The bombesin group of hormonal peptides produced in the amphibian skin have powerful actions on the mammalian gastrointestinal tract. In man a bombesin-like material was found in an endocrine cell which is widely distributed in the gastrointestinal mucosa. This has tentatively been identified as belonging to the non-enterochromaffin cell groups. The large number of cells containing a bombesin-like peptide suggests that this substance may be important in human physiology.
MeSH terms
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Brunner Glands / cytology
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Colon / cytology
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Duodenum / cytology
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Fluorescent Antibody Technique
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Gastric Mucosa / cytology
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Gastric Mucosa / metabolism*
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Gastrointestinal Hormones / isolation & purification*
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Gastrointestinal Hormones / physiology
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Histocytochemistry
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Humans
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Ileum / cytology
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Intestinal Mucosa / cytology
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Intestinal Mucosa / metabolism*
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Jejunum / cytology
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Peptides / isolation & purification*
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Peptides / physiology
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Staining and Labeling
Substances
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Gastrointestinal Hormones
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Peptides