Diagnosis and treatment of a carcinoid tumor using iodine-131 meta-iodobenzylguanidine

Clin Nucl Med. 1986 Mar;11(3):150-2. doi: 10.1097/00003072-198603000-00002.

Abstract

Scintigraphy using I-131 meta-iodobenzylguanidine has been introduced as an effective method to detect pheochromocytomas and neuroblastomas, and the radiopharmaceutical also is applied in therapy of these tumors. The authors present a case of a metastatic gastric carcinoid tumor, another neural crest tumor, concentrating I-131 MIBG, which was documented by conventional scintigraphy and SPECT in correlation with CT scans and colloid scintigrams of the liver. Two therapeutic attempts in this patient, using I-131 MIBG, are described. The metabolic basis of this phenomenon is discussed, and the importance of I-131 MIBG imaging in the detection of neural crest tumors is underlined.

Publication types

  • Case Reports

MeSH terms

  • 3-Iodobenzylguanidine
  • Adult
  • Carcinoid Tumor / diagnostic imaging
  • Carcinoid Tumor / radiotherapy
  • Carcinoid Tumor / secondary*
  • Female
  • Humans
  • Iodine Radioisotopes / therapeutic use*
  • Iodobenzenes*
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / radiotherapy
  • Liver Neoplasms / secondary*
  • Radionuclide Imaging
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / radiotherapy

Substances

  • Iodine Radioisotopes
  • Iodobenzenes
  • 3-Iodobenzylguanidine