68Ga-PSMA PET/CT: Joint EANM and SNMMI procedure guideline for prostate cancer imaging: version 1.0

Wolfgang P Fendler; Matthias Eiber; Mohsen Beheshti; Jamshed Bomanji; Francesco Ceci; Steven Cho; Frederik Giesel; Uwe Haberkorn; Thomas A Hope; Klaus Kopka; Bernd J Krause; Felix M Mottaghy; Heiko Schöder; John Sunderland; Simon Wan; Hans-Jürgen Wester; Stefano Fanti; Ken Herrmann

doi:10.1007/s00259-017-3670-z

⁶⁸Ga-PSMA PET/CT: Joint EANM and SNMMI procedure guideline for prostate cancer imaging: version 1.0

Eur J Nucl Med Mol Imaging. 2017 Jun;44(6):1014-1024. doi: 10.1007/s00259-017-3670-z.

Authors

Wolfgang P Fendler^{1

2}, Matthias Eiber^{1

3}, Mohsen Beheshti⁴, Jamshed Bomanji⁵, Francesco Ceci⁶, Steven Cho⁷, Frederik Giesel⁸, Uwe Haberkorn⁸, Thomas A Hope⁹, Klaus Kopka¹⁰, Bernd J Krause¹¹, Felix M Mottaghy^{12

13}, Heiko Schöder¹⁴, John Sunderland¹⁵, Simon Wan⁵, Hans-Jürgen Wester¹⁶, Stefano Fanti⁶, Ken Herrmann^{17

18}

Affiliations

¹ Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, 10833 Le Conte Ave, 200 Medical Plaza, Los Angeles, CA, USA.
² Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
³ Department of Nuclear Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
⁴ Department of Nuclear Medicine & Endocrinology, PET-CT Center, St. Vincent's Hospital, Linz, Austria.
⁵ Institute of Nuclear Medicine, UCL/UCLH, London, UK.
⁶ Nuclear Medicine Unit, University of Bologna, S. Orsola Hospital Bologna, Bologna, Italy.
⁷ Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
⁸ Department of Nuclear Medicine, University Hospital Heidelberg and DKFZ Heidelberg, Heidelberg, Germany.
⁹ Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
¹⁰ Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
¹¹ Department of Nuclear Medicine, University Medical Center, University of Rostock, Rostock, Germany.
¹² Department of Nuclear Medicine, University Hospital RWTH Aachen University, Aachen, Germany.
¹³ Department of Nuclear Medicine, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
¹⁴ Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
¹⁵ Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
¹⁶ Pharmaceutical Radiochemistry, Technische Universität München, Walther-Meißner-Str.3, 85748, Garching, Germany.
¹⁷ Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, 10833 Le Conte Ave, 200 Medical Plaza, Los Angeles, CA, USA. kherrmann@mednet.ucla.edu.
¹⁸ Klinik für Nuklearmedizin, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Germany. kherrmann@mednet.ucla.edu.

PMID: 28283702
DOI: 10.1007/s00259-017-3670-z

Abstract

The aim of this guideline is to provide standards for the recommendation, performance, interpretation and reporting of ⁶⁸Ga-PSMA PET/CT for prostate cancer imaging. These recommendations will help to improve accuracy, precision, and repeatability of ⁶⁸Ga-PSMA PET/CT for prostate cancer essentially needed for implementation of this modality in science and routine clinical practice.

Keywords: Guideline; PET; PSMA; Prostate cancer; Restaging; Staging.

MeSH terms

Antigens, Surface* / metabolism
Europe
Gallium Radioisotopes*
Glutamate Carboxypeptidase II* / metabolism
Humans
Ligands
Male
Nuclear Medicine*
Positron Emission Tomography Computed Tomography / methods*
Practice Guidelines as Topic*
Prostatic Neoplasms / diagnostic imaging*
Prostatic Neoplasms / metabolism
Radiation Exposure / adverse effects
Research Report
Societies, Medical*

Substances

Antigens, Surface
Gallium Radioisotopes
Ligands
FOLH1 protein, human
Glutamate Carboxypeptidase II