Partial Volume Correction Strategies in PET

Olivier Rousset; Arman Rahmim; Abass Alavi; Habib Zaidi

doi:10.1016/j.cpet.2007.10.005

Partial Volume Correction Strategies in PET

PET Clin. 2007 Apr;2(2):235-49. doi: 10.1016/j.cpet.2007.10.005. Epub 2008 Feb 15.

Authors

Olivier Rousset¹, Arman Rahmim², Abass Alavi³, Habib Zaidi⁴

Affiliations

¹ Division of Nuclear Medicine, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Johns Hopkins Outpatient Centre, Room 3245, 601 N. Caroline St., Baltimore, MD 21287, USA. Electronic address: olivier@jhu.edu.
² Division of Nuclear Medicine, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Johns Hopkins Outpatient Centre, Room 3245, 601 N. Caroline St., Baltimore, MD 21287, USA.
³ Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
⁴ Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva, Switzerland.

PMID: 27157875
DOI: 10.1016/j.cpet.2007.10.005

Abstract

In the early days of PET, the partial volume effect (PVE) was identified as a serious factor affecting image quality and limiting the accuracy of quantitative analysis. Because of the limited spatial resolution of clinical PET systems, the images are blurred by the system response so that smaller objects appear larger. Although the total number of counts is preserved, they are distributed over a larger volume. This article describes the various partial volume correction strategies used in PET and summarizes their clinical and research applications.

Publication types

Review

Grants and funding

R21 AG056142/AG/NIA NIH HHS/United States