Abstract
A close spatial relationship between serotonin-containing mast cells and substance P-containing nerves was shown by immunohistochemistry using a combination of antisera specific for serotonin and substance P. This supports earlier morphological results suggesting an innervation of mast cells and pharmacological studies which postulate an influence of substance P on the release of histamine from mast cells.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Diaphragm / anatomy & histology*
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Histocytochemistry
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Immune Sera
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Male
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Mast Cells / analysis
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Mast Cells / physiology*
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Mesentery / anatomy & histology*
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Nerve Fibers / analysis
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Nerve Fibers / physiology*
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Rats
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Rats, Inbred Strains
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Serotonin / analysis
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Staining and Labeling
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Substance P / analysis
Substances
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Immune Sera
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Serotonin
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Substance P