Optimization of prostate biopsy: review of technique and complications

Urol Clin North Am. 2014 May;41(2):299-313. doi: 10.1016/j.ucl.2014.01.011.

Abstract

A 12-core systematic biopsy that incorporates apical and far-lateral cores in the template distribution allows maximal cancer detection and avoidance of a repeat biopsy while minimizing the detection of insignificant prostate cancers. Magnetic resonance imaging-guided prostate biopsy has an evolving role in both initial and repeat prostate biopsy strategies, potentially improving sampling efficiency, increasing the detection of clinically significant cancers, and reducing the detection of insignificant cancers. Hematuria, hematospermia, and rectal bleeding are common complications of prostate needle biopsy, but are generally self-limiting and well tolerated. All men should receive antimicrobial prophylaxis before biopsy.

Keywords: Biopsy core number; Magnetic resonance imaging; Prostate needle biopsy; Quinolone-reistant infection.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Early Detection of Cancer / adverse effects*
  • Early Detection of Cancer / methods*
  • Humans
  • Image-Guided Biopsy / trends*
  • Magnetic Resonance Imaging / trends*
  • Male
  • Prostate / pathology*
  • Prostatic Neoplasms / diagnosis*
  • Reproducibility of Results