Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

MAGMA. 2013 Feb;26(1):173-81. doi: 10.1007/s10334-012-0345-4. Epub 2012 Sep 21.

Abstract

Purpose: Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood.

Results: Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system.

Conclusion: A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.

MeSH terms

  • Algorithms
  • Artifacts*
  • Fluorodeoxyglucose F18
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed
  • Whole Body Imaging

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18