Changes of the normal ovary during menstrual cycle in reproductive age on the diffusion-weighted image

J Comput Assist Tomogr. 2012 May-Jun;36(3):319-22. doi: 10.1097/RCT.0b013e318255aebf.

Abstract

Objective: The objective of this study was to investigate changes in magnetic resonance findings of the normal ovary during menstrual cycle on diffusion-weighted image (DWI).

Methods: Magnetic resonance imaging was performed in 9 healthy females at the menstrual, periovulatory, and luteal phases using a 1.5-T unit. Signal intensity (SI) of the ovary on DWI with a b value of 1000 s/mm was visually scored. The ovary-to-muscle contrast ratios on DWI and apparent diffusion coefficient (ADC) values were also evaluated.

Results: All the ovaries were identified, and higher SI than the nerve root was identified in 70% (38/54) of the ovaries, although visual scores did not show significant difference among menstrual phases. The mean ADC values (10 mm/s) were 1.71 (SD, 0.27), 1.71 (SD, 0.22), and 1.67 (SD, 0.19) in menstrual, periovulatory, and luteal phases, respectively. No phase-dependent change was observed in contrast ratios and ADC values.

Conclusion: The normal ovary in fertile period shows high SI enough to be identified on DWI, and observed values are independent of the menstrual cycle.

MeSH terms

  • Adult
  • Analysis of Variance
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Menstrual Cycle*
  • Observer Variation
  • Ovary / anatomy & histology*
  • Prospective Studies
  • Reference Values
  • Young Adult