Impact of iterative reconstruction on image quality and radiation dose in multidetector CT of large body size adults

Eur Radiol. 2012 Aug;22(8):1631-40. doi: 10.1007/s00330-012-2424-3. Epub 2012 Apr 19.

Abstract

Objective: To compare image quality and radiation dose using Adaptive Statistical Iterative Reconstruction (ASiR) and Filtered Back Projection (FBP) in patients weighing ≥ 91 kg.

Methods: In this Institution Review Board-approved retrospective study, single-phase contrast-enhanced abdominopelvic CT examinations of 100 adults weighing ≥ 91 kg (mean body weight: 107.6 ± 17.4 kg range: 91-181.9 kg) with (1) ASiR and (2) FBP were reviewed by two readers in a blinded fashion for subjective measures of image quality (using a subjective standardized numerical scale and objective noise) and for radiation exposure. Imaging parameters and radiation dose results of the two techniques were compared within weight and BMI sub-categories.

Results: All examinations were found to be of adequate quality. Both subjective (mean = 1.4 ± 0.5 vs. 1.6 ± 0.6, P < 0.05) and objective noise (13.0 ± 3.2 vs.19.5 ± 5.7, P < 0.0001) were lower with ASiR. Average radiation dose reduction of 31.5 % was achieved using ASiR (mean CTDIvol. ASiR: 13.5 ± 7.3 mGy; FBP: 19.7 ± 9.0 mGy, P < 0.0001). Other measures of image quality were comparable between the two techniques. Trends for all parameters were similar in patients across weight and BMI sub-categories.

Conclusion: In obese individuals, abdominal CT images reconstructed using ASiR provide diagnostic images with reduced image noise at lower radiation dose.

Key points: • CT images in obese adults are noisy, even with high radiation dose. • Newer iterative reconstruction techniques have theoretical advantages in obese patients. • Adaptive statistical iterative reconstruction should reduce image noise and radiation dose. • This has been proven in abdominopelvic CT images of obese patients.

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Body Size
  • Body Weight
  • Contrast Media / administration & dosage
  • Female
  • Humans
  • Infusions, Intravenous
  • Male
  • Medical Records Systems, Computerized
  • Microscopy, Phase-Contrast / methods
  • Middle Aged
  • Obesity
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media